用于矫正耳聋的基础编辑器

IF 26.8 1区医学 Q1 ENGINEERING, BIOMEDICAL

Nature Biomedical Engineering Pub Date : 2024-08-12 DOI:10.1038/s41551-024-01234-2

Bence György

引用次数: 0

摘要

碱基编辑可纠正小鼠的听力损失表型，这种小鼠携带一种常见的奥托菲林基因突变。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

A base editor for correcting deafness

查看原文本刊更多论文

A base editor for correcting deafness

Base editing can correct the hearing-loss phenotype in mice harbouring a common mutation in the otoferlin gene.

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来源期刊

Nature Biomedical Engineering Medicine-Medicine (miscellaneous)

CiteScore

45.30

自引率

1.10%

发文量

138

期刊介绍： Nature Biomedical Engineering is an online-only monthly journal that was launched in January 2017. It aims to publish original research, reviews, and commentary focusing on applied biomedicine and health technology. The journal targets a diverse audience, including life scientists who are involved in developing experimental or computational systems and methods to enhance our understanding of human physiology. It also covers biomedical researchers and engineers who are engaged in designing or optimizing therapies, assays, devices, or procedures for diagnosing or treating diseases. Additionally, clinicians, who make use of research outputs to evaluate patient health or administer therapy in various clinical settings and healthcare contexts, are also part of the target audience.