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白细胞介素-21 工程通过 CEBPD 增强 NK 细胞抗胶质母细胞瘤的活性

IF 48.8 1区 医学 Q1 CELL BIOLOGY
Cancer Cell Pub Date : 2024-08-12 DOI:10.1016/j.ccell.2024.07.007
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引用次数: 0

摘要

胶质母细胞瘤（GBM）是一种侵袭性脑癌，治疗方案有限。自然杀伤（NK）细胞是一种先天性免疫细胞，具有很强的抗...
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Interleukin-21 engineering enhances NK cell activity against glioblastoma via CEBPD
Glioblastoma (GBM) is an aggressive brain cancer with limited therapeutic options. Natural killer (NK) cells are innate immune cells with strong anti-…
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来源期刊
Cancer Cell
Cancer Cell 医学-肿瘤学
CiteScore
55.20
自引率
1.20%
发文量
179
审稿时长
4-8 weeks
期刊介绍： Cancer Cell is a journal that focuses on promoting major advances in cancer research and oncology. The primary criteria for considering manuscripts are as follows: Major advances: Manuscripts should provide significant advancements in answering important questions related to naturally occurring cancers. Translational research: The journal welcomes translational research, which involves the application of basic scientific findings to human health and clinical practice. Clinical investigations: Cancer Cell is interested in publishing clinical investigations that contribute to establishing new paradigms in the treatment, diagnosis, or prevention of cancers. Insights into cancer biology: The journal values clinical investigations that provide important insights into cancer biology beyond what has been revealed by preclinical studies. Mechanism-based proof-of-principle studies: Cancer Cell encourages the publication of mechanism-based proof-of-principle clinical studies, which demonstrate the feasibility of a specific therapeutic approach or diagnostic test.
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