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引用次数: 0
摘要
退稿：X. Zhong, X. Wen, L. Chen, N. Gu, X. Yu, and K. Sui, "Long non-coding RNA KCNQ1OT1 Promotes the Progression of Gastric Cancer via the miR-145-5p/ARF6 Axis," The Journal of Gene Medicine 23, no.5 (2021): e3330, https://doi.org/10.1002/jgm.3330.The 上述文章于 2021 年 3 月 8 日在线发表于 Wiley Online Library (wileyonlinelibrary.com)，经期刊主编 Jiang Fan 和 John Wiley & Sons Ltd.同意，已被撤回。之所以同意撤稿，是因为第三方对文章中提供的数据提出了疑虑。我们发现，文章所展示的结果与实验方法之间存在若干缺陷和不一致之处。具体而言，发现多个图像元素已在其他地方的不同科学背景下发表。此外，文章还介绍了多个不可验证/未知细胞系的结果：BSG823、BSG803、BGC803 和 GSE1。因此，编辑认为这篇文章的结论无效。作者已被告知撤稿决定，但无法得到最终确认。
RETRACTION: Long non-coding RNA KCNQ1OT1 Promotes the Progression of Gastric Cancer via the miR-145-5p/ARF6 Axis
RETRACTION: X. Zhong, X. Wen, L. Chen, N. Gu, X. Yu, and K. Sui, “Long non-coding RNA KCNQ1OT1 Promotes the Progression of Gastric Cancer via the miR-145-5p/ARF6 Axis,” The Journal of Gene Medicine 23, no. 5 (2021): e3330, https://doi.org/10.1002/jgm.3330.
The above article, published online on 8 March 2021 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Jiang Fan; and John Wiley & Sons Ltd. The retraction has been agreed due to concerns raised by third parties on the data presented in the article. Several flaws and inconsistencies between results presented and experimental methods described were found. Specifically, multiple image elements were found to have been published elsewhere in a different scientific context. Furthermore, the article presents results from multiple non-verifiable/unknown cell lines: BSG823, BSG803, BGC803, and GSE1. Accordingly, the conclusions of this article are considered invalid by the editors. The authors have been informed of the decision of retraction but unavailable for a final confirmation.
期刊介绍：
The aims and scope of The Journal of Gene Medicine include cutting-edge science of gene transfer and its applications in gene and cell therapy, genome editing with precision nucleases, epigenetic modifications of host genome by small molecules, siRNA, microRNA and other noncoding RNAs as therapeutic gene-modulating agents or targets, biomarkers for precision medicine, and gene-based prognostic/diagnostic studies.
Key areas of interest are the design of novel synthetic and viral vectors, novel therapeutic nucleic acids such as mRNA, modified microRNAs and siRNAs, antagomirs, aptamers, antisense and exon-skipping agents, refined genome editing tools using nucleic acid /protein combinations, physically or biologically targeted delivery and gene modulation, ex vivo or in vivo pharmacological studies including animal models, and human clinical trials.
Papers presenting research into the mechanisms underlying transfer and action of gene medicines, the application of the new technologies for stem cell modification or nucleic acid based vaccines, the identification of new genetic or epigenetic variations as biomarkers to direct precision medicine, and the preclinical/clinical development of gene/expression signatures indicative of diagnosis or predictive of prognosis are also encouraged.
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