间歇性外斜儿童的适应性和辐辏与轴长伸长的关系:一项为期 12 个月的观察研究。

IF 2 4区 医学 Q2 OPHTHALMOLOGY
Ophthalmic Research Pub Date : 2024-01-01 Epub Date: 2024-08-07 DOI:10.1159/000540154
Jing-Xin Li, Jie Hao, Xiang-Xiang Liu, Jie Hong, Hui-Xin Li, Qiong-Yue Zhang, Yi-Yang Zhao, Lei Li, Jing Fu
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引用次数: 0

摘要

引言研究基础间歇性外斜视(IXT)患者的适应、辐辏和轴伸长相关参数的关联,以及轴长(AL)增长的潜在临床预测因素:本研究共招募了140名基础性间歇性外斜患者。选择不同年龄段AL增长的中位数,将受试者分为A组(轴向伸长较慢组,69人)和B组(轴向伸长较快组,71人)。在 12 个月的随访期间,对优势眼和非优势眼的参数进行比较和分析。这些参数包括基线屈光度、偏差角、纽卡斯尔评分(NCS)、适应振幅(AMP)、适应设施(AMF)、适应反应、正或负相对适应(PRA/NRA)以及近辐辏点(NPC),通过单变量和多变量回归进行分析:结果:与轴向拉长较慢组相比,轴向拉长较快组的受试者往往有更多的近视球面等值(t=3.956,P<.001)、更大的优势眼适应振幅(t=-2.238,P=.027)和更少的近辐辏点(t=2.347,P=.020)。对于显性眼,逻辑和线性回归分析表明,更多的负球面等值(OR=0.603,P<.001;β=-0.045,P<.001)、更大的容纳幅度(OR=1.201,P=.027;β=0.023,P=.010)和更少的近辐辏点(OR=0.883,P=.021;β=-0.012,P=.019)与轴伸长更快的组相关。对于非优势眼,通过回归分析,更多的近视球面等值(OR=0.682;P=.001;β=-0.029,P=.005)是唯一与更快的轴伸长相关的参数:结论:在患有基本间歇性外斜的儿童中,优势眼轴伸长较快与更多近视球面等值物、更大的容纳振幅和更低的近辐辏点有关。除轴长外,这些适应参数可作为监测近视进展的潜在临床指标。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Association of Accommodation and Convergence with Axial Length Elongation in Children with Basic Intermittent Exotropia: A 12-Month Observational Study.

Introduction: The aim of the study was to investigate the association of parameters related to accommodation and convergence and axial elongation in basic intermittent exotropia (IXT) patients and the potential clinical predictors of axial length (AL) growth.

Methods: A total of 140 basic IXT patients were recruited in this study. The medians of AL growth in different age brackets were chosen to divide the subjects into group A (slower axial elongation group, n = 69) and group B (faster axial elongation group, n = 71). Parameters of dominant and nondominant eyes were compared and analyzed during the 12-month follow-up period. The parameters, including baseline refraction, angle of deviation, Newcastle control score (NCS), accommodative amplitude (AMP), accommodative facility (AMF), accommodative response, positive or negative relative accommodation (PRA/NRA), and near point of convergence (NPC), were analyzed via univariate and multivariate regression.

Results: Subjects in the faster axial elongation group tended to have more myopic spherical equivalents (t = 3.956, p < 0.001), greater AMPs of dominant eyes (t = -2.238, p = 0.027), and fewer near points of convergence (t = 2.347, p = 0.020) than in the slower axial elongation group. For dominant eyes, logistic and linear regression analysis revealed that more negative spherical equivalents (OR = 0.603, p < 0.001; β = -0.045, p < 0.001), greater AMPs (OR = 1.201, p = 0.027; β = 0.023, p = 0.010), and less near points of convergence (OR = 0.883, p = 0.021; β = -0.012, p = 0.019) were correlated with the faster axial elongation. For nondominant eyes, a more myopic spherical equivalent (OR = 0.682; p = 0.001; β = -0.029, p = 0.005) was the only parameter correlated with faster axial elongation through regression analysis.

Conclusion: In children with basic IXT, faster axial elongation in the dominant eyes was associated with more myopic spherical equivalents, greater AMPs, and lower NPCs. These accommodative parameters can serve as potential clinical indicators for monitoring myopia progression in addition to AL.

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来源期刊
Ophthalmic Research
Ophthalmic Research 医学-眼科学
CiteScore
3.80
自引率
4.80%
发文量
75
审稿时长
6-12 weeks
期刊介绍: ''Ophthalmic Research'' features original papers and reviews reporting on translational and clinical studies. Authors from throughout the world cover research topics on every field in connection with physical, physiologic, pharmacological, biochemical and molecular biological aspects of ophthalmology. This journal also aims to provide a record of international clinical research for both researchers and clinicians in ophthalmology. Finally, the transfer of information from fundamental research to clinical research and clinical practice is particularly welcome.
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