MRgFUS 在治疗神经精神疾病中的作用:最新进展。

IF 1.3 4区 医学 Q4 CLINICAL NEUROLOGY
Benedetta M Campisi, Roberta Costanzo, Manfredi Noto, Giuseppe P Cipollina, Silvia Marino, Giuseppe DI Lorenzo, Lapo Bonosi, Lara Brunasso, Domenico G Iacopino, Rosario Maugeri
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引用次数: 0

摘要

导言:磁共振引导下聚焦超声(MRgFUS)是一种现代无创消融术,它利用高强度或低强度超声,在磁共振成像(MRI)的引导和监控下进行。磁共振聚焦超声已被确定为治疗本质性震颤和以震颤为主的帕金森病等疾病的有效方法,最近它又成为治疗耐药性精神疾病的一种安全、有前景的微创消融术。事实上,尽管有各种药物和行为疗法,但仍有一部分精神病患者对传统疗法难治:为了评估 MRgFUS 治疗精神疾病的可行性和安全性,我们在 PubMed 和 Scopus 数据库中进行了全面的文献检索,最终将五篇相关文章纳入本综述:虽然有关这种创新手术的数据仍然有限,但 MRgFUS 显示出作为一种更安全、创伤更小的手术技术治疗这些疾病的潜力:要在不久的将来将 MRgFUS 确立为治疗耐药精神病患者的另一种微创手术,继续开展研究工作和数据验证势在必行。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The role of MRgFUS in the treatment of neuropsychiatric disorders: a state of the art.

Introduction: Magnetic resonance-guided focused ultrasound (MRgFUS) is a contemporary non-invasive ablative procedure that utilizes high- or low-intensity ultrasound, guided and monitored by magnetic resonance imaging (MRI). While MRgFUS has been established as an effective treatment for conditions like essential tremor and tremor-dominant Parkinson's disease, it has recently emerged as a safe and promising ablative minimally invasive procedure for the management of treatment-resistant psychiatric disorders. Indeed, despite the availability of various pharmacological and behavioral therapies, a subset of psychiatric patients remains refractory to conventional treatments.

Evidence acquisition: To assess the feasibility and safety of MRgFUS in psychiatric disorders, a comprehensive literature search in PubMed and Scopus databases was conducted, resulting in the inclusion of five relevant articles in this review.

Evidence synthesis: While data on this innovative procedure are still limited, MRgFUS demonstrates potential as a safer and less invasive surgical technique for treating these disorders.

Conclusions: Continued research efforts and data validation are imperative to establish MRgFUS as an additional, minimally invasive procedure for treatment-resistant psychiatric patients in the near future.

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来源期刊
Journal of neurosurgical sciences
Journal of neurosurgical sciences CLINICAL NEUROLOGY-SURGERY
CiteScore
3.00
自引率
5.30%
发文量
202
审稿时长
>12 weeks
期刊介绍: The Journal of Neurosurgical Sciences publishes scientific papers on neurosurgery and related subjects (electroencephalography, neurophysiology, neurochemistry, neuropathology, stereotaxy, neuroanatomy, neuroradiology, etc.). Manuscripts may be submitted in the form of ditorials, original articles, review articles, special articles, letters to the Editor and guidelines. The journal aims to provide its readers with papers of the highest quality and impact through a process of careful peer review and editorial work.
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