一名肺动脉闭锁伴室间隔缺损手术后接受达克龙® 萨诺分流术的患儿在接受阿卓那姆-阿维巴坦联合疗法治疗后，由 NDM-1 型大肠埃希菌引起的纵隔炎。

IF 4.9 2区医学 Q1 INFECTIOUS DISEASES

International Journal of Antimicrobial Agents Pub Date : 2024-08-02 DOI:10.1016/j.ijantimicag.2024.107295

Vladimir L. Cousin , Jordi Miatello , Roberto Sierra , Tornike Sologashvili , Julie Wacker , Diego O. Andrey , Arnaud G. L'Huillier

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引用次数: 0

摘要

耐碳青霉烯类肠杆菌的报道越来越多，这些肠杆菌引起的院内感染可能包括术后纵隔炎。在此，我们报告了一起由大肠埃希菌 NDM-1 碳青霉烯酶生产者引起的术后纵隔炎，患者是一名 13 个月大的迪乔治综合征男孩。感染经过手术清创和使用阿曲南钠、头孢唑肟-阿维巴坦和静脉注射磷霉素 6 周的抗生素治疗后得到控制。随访 10 周后，病情发展良好，没有复发。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Mediastinitis caused by an NDM-1 Escherichia coli in a child with Dacron Sano shunt after pulmonary atresia with ventricular septal defect surgery treated with combination of aztreonam-avibactam

Carbapenem-resistant Enterobacterales are being reported increasingly and cause nosocomial infections, which may include postoperative mediastinitis. This paper reports a case of postoperative mediastinitis caused by an Escherichia coli NDM-1 carbapenemase producer in a 13-month-old boy with DiGeorge syndrome. The infection was managed with surgical debridement and antibiotherapy with aztreonam, ceftazidime-avibactam and IV fosfomycin for 6 weeks. The evolution was favourable, without relapse over 10 weeks of follow-up.

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来源期刊

International Journal of Antimicrobial Agents 医学-传染病学

CiteScore

21.60

自引率

0.90%

发文量

176

审稿时长

36 days

期刊介绍： The International Journal of Antimicrobial Agents is a peer-reviewed publication offering comprehensive and current reference information on the physical, pharmacological, in vitro, and clinical properties of individual antimicrobial agents, covering antiviral, antiparasitic, antibacterial, and antifungal agents. The journal not only communicates new trends and developments through authoritative review articles but also addresses the critical issue of antimicrobial resistance, both in hospital and community settings. Published content includes solicited reviews by leading experts and high-quality original research papers in the specified fields.