妊娠与癌症之间存在共同的免疫抑制机制。

IF 72.5 1区医学 Q1 ONCOLOGY

Nature Reviews Cancer Pub Date : 2024-08-01 DOI:10.1038/s41568-024-00731-5

Linda Gummlich

引用次数: 0

摘要

妊娠涉及免疫系统抑制以保护胎儿，因此是了解癌症免疫耐受的一个宝贵模型。最近，Yu 等人在《细胞》（Cell）杂志上发现，B7-H4 是肿瘤和胎盘中常见的免疫耐受检查点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Shared immunosuppressive mechanism between pregnancy and cancer

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Shared immunosuppressive mechanism between pregnancy and cancer

Pregnancy involves immune system suppression to protect the fetus, making it a valuable model for understanding cancer immune tolerance. Recently in Cell, Yu et al. identified B7-H4 as a common immune tolerance checkpoint in both tumours and the placenta.

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来源期刊

Nature Reviews Cancer 医学-肿瘤学

CiteScore

111.90

自引率

0.40%

发文量

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Cancer, a part of the Nature Reviews portfolio of journals, aims to be the premier source of reviews and commentaries for the scientific communities it serves. The correct abbreviation for abstracting and indexing purposes is Nat. Rev. Cancer. The international standard serial numbers (ISSN) for Nature Reviews Cancer are 1474-175X (print) and 1474-1768 (online). Unlike other journals, Nature Reviews Cancer does not have an external editorial board. Instead, all editorial decisions are made by a team of full-time professional editors who are PhD-level scientists. The journal publishes Research Highlights, Comments, Reviews, and Perspectives relevant to cancer researchers, ensuring that the articles reach the widest possible audience due to their broad scope.