在超声心动图正常的健康成年波尔佐伊犬中,经常会发现心电图异常。

IF 1.6 2区 农林科学 Q2 VETERINARY SCIENCES
Sonya Wesselowski, Blakeley Janacek, K Tess Sykes, Ashley B Saunders
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引用次数: 0

摘要

目标:据报道,博佐伊犬会发生猝死。本研究旨在报告临床健康博柔犬的心电图间隔、振幅和心电图异常频率。方法:在 2020 年 10 月至 2022 年 12 月期间,前瞻性地招募了 98 只临床健康博柔犬,并对其进行了超声心动图、心电图和心肌肌钙蛋白 I 检测。获得标准心电图测量结果。结果:在 82 只超声心动图结构正常的博尔佐伊犬中,有 8 只(10%)记录到室性心律失常,所有这些犬的心肌肌钙蛋白 I 浓度均正常。P 波持续时间中位数为 55 毫秒(范围为 45 至 70 毫秒)。PR 间期中位数为 125 毫秒(范围为 80 至 175 毫秒)。31只(38%)博尔佐伊犬患有一级房室传导阻滞(PR间期大于130毫秒)。QRS 中位持续时间为 65 毫秒(范围为 48 至 90 毫秒)。QT 间期中位数为 235 毫秒(范围为 185 至 275 毫秒)。82 只博尔佐犬中分别有 29 只(35%)和 15 只(18%)的 QT 间期大于 240 或大于 250 毫秒。82 只博尔佐犬中有 67 只(82%)出现了早期再极化缺口或斜线。82 只博尔佐伊犬中有 17 只(21%)ST 段异常,最常见的是前凸/后凹。ST 段的凸度为间歇性(9 例)或持续性(4 例):结论:室性心律失常、早复极、QT 间期延长和 ST 段异常在临床健康的博尔佐犬中并不少见。与一般犬类的参考间期相比,P、PR 和 QRS 持续时间普遍延长:临床意义:鉴于博尔佐伊犬经常出现室性心律失常、再极化异常和猝死,今后有必要对该犬种的遗传性通道病进行研究。需要制定针对特定犬种的心电图参考区间。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Electrocardiographic abnormalities are frequently detected in healthy adult Borzoi with a normal echocardiogram.

Objective: Borzoi reportedly experience sudden death. The objective of this study was to report ECG intervals, amplitudes, and frequency of ECG abnormalities in clinically healthy Borzoi.

Methods: 98 clinically healthy Borzoi were prospectively recruited and underwent echocardiogram, ECG, and cardiac troponin I testing between October 2020 and December 2022. Standard ECG measurements were obtained. Early repolarization notches and slurs were recorded.

Results: Of 82 Borzoi with a structurally normal echocardiogram, ventricular arrhythmias were documented in 8 (10%) dogs, all of which had normal cardiac troponin I concentrations. Median P wave duration was 55 milliseconds (range, 45 to 70 milliseconds). Median PR interval was 125 milliseconds (range, 80 to 175 milliseconds). Thirty-one (38%) Borzoi had first-degree atrioventricular block (PR interval > 130 milliseconds). Median QRS duration was 65 milliseconds (range, 48 to 90 milliseconds). Median QT interval was 235 milliseconds (range, 185 to 275 milliseconds). Twenty-nine (35%) and 15 (18%) of 82 Borzoi had QT intervals > 240 or > 250 milliseconds, respectively. Sixty-seven of 82 (82%) Borzoi had early repolarization notches or slurs. Seventeen of 82 (21%) Borzoi had an abnormality of the ST segment, most commonly convexity/doming. Convexity of the ST segment was intermittent (n = 9) or persistent (4).

Conclusions: Ventricular arrhythmias, early repolarization, prolonged QT intervals, and ST segment abnormalities are not infrequent in clinically healthy Borzoi. P, PR, and QRS durations are commonly prolonged compared to general canine reference intervals.

Clinical relevance: Future study into heritable channelopathies in Borzoi is warranted given the frequency of ventricular arrhythmias, repolarization abnormalities, and sudden death in the breed. Breed-specific ECG reference intervals are needed.

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来源期刊
CiteScore
1.60
自引率
15.80%
发文量
539
审稿时长
6-16 weeks
期刊介绍: Published twice monthly, this peer-reviewed, general scientific journal provides reports of clinical research, feature articles and regular columns of interest to veterinarians in private and public practice. The News and Classified Ad sections are posted online 10 days to two weeks before they are delivered in print.
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