增殖性糖尿病视网膜病变的临床特征和增殖性糖尿病视网膜病变玻璃体旁切除术的疗效

Q3 Medicine

Journal of Nepal Health Research Council Pub Date : 2024-06-22 DOI:10.33314/jnhrc.v22i01.4958

Raba Thapa, Sanjita Sharma, Eli Pradhan, Sushma Duwal, Govinda Paudyal

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引用次数: 0

摘要

背景：增殖性糖尿病视网膜病变是导致糖尿病患者失明的主要原因。该研究旨在评估增殖性糖尿病视网膜病变的临床特征和增殖性糖尿病视网膜病变玻璃体旁切除术的结果：2019年9月至2021年12月，在一家三级眼科医疗中心对接受玻璃体旁切除术的增殖性糖尿病视网膜病变连续病例进行了前瞻性研究。研究在获得机构审查委员会的伦理批准后进行。研究详细记录了患者的系统和眼部病史、视力、瞳孔散大时的眼部检查结果、手术过程以及玻璃体旁切除术后的结果。对病例进行定期随访，直至玻璃体旁切除术后一年：共有 83 例（89 只眼）增殖性糖尿病视网膜病变患者参与了研究。平均年龄为 53 岁（±9.7 SD），从 26 岁到 72 岁不等。男性占 62.7%。二型糖尿病患者占 94%。玻璃体旁切除术的适应症包括：混合性玻璃体出血和牵引性视网膜脱离（38.2%）、非清扫性玻璃体出血（38.1%）和仅牵引性视网膜脱离（24.7%）。78.65%的患者术前在玻璃体内注射了抗血管内皮生长因子，58.42%的患者进行了泛视网膜光凝。95.5%的眼睛获得了解剖学上的成功，68.54%的眼睛视力得到改善，14.6%的眼睛视力保持不变，16.86%的眼睛视力恶化。约 15.7% 的眼睛出现了某种形式的术后并发症：结论：在增殖性糖尿病视网膜病变病例中，玻璃体出血伴牵引性视网膜脱离、持续性玻璃体出血和涉及黄斑的牵引性视网膜脱离是平面旁玻璃体切除术的常见适应症。大多数增殖性糖尿病视网膜病变患者在接受玻璃体切割术后都能获得解剖学上的成功和视力的改善。

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Clinical Characteristics of Proliferative Diabetic Retinopathy and Outcome of Pars Plana Vitrectomy in Proliferative Diabetic Retinopathy.

Background: Proliferative diabetic retinopathy is a leading cause of blindness among people with diabetes. The study aimed to assess the clinical characteristics of proliferative diabetic retinopathy and outcome of pars plana vitrectomy in Proliferative diabetic retinopathy.

Methods: A prospective study was conducted from September 2019 to December 2021 among consecutive cases of proliferative diabetic retinopathy who underwent pars plana vitrectomy at a tertiary eye care center. Study was conducted after ethical approval from Institutional Review Committee. Detailed systemic and ocular history, visual acuity, ocular findings under mydriasis, surgical procedures, and outcome following pars plana vitrectomy were recorded. Cases were followed up regularly until one year after the pars plana vitrectomy.

Results: Total of 83 cases (89 eyes) of proliferative diabetic retinopathy were enrolled in the study. The mean age was 53 years ±9.7 SD, ranging from 26 years to 72 years. Males comprised of 62.7% cases. Type two diabetes comprised of 94% of cases. Indications for pars plana vitrectomy were; mixed vitreous hemorrhage and tractional retinal detachment (38.2%), non-clearing vitreous hemorrhage (38.1%), and tractional retinal detachment only (24.7%). Pre-operative intra-vitreal anti-vascular endothelial growth factor was given in 78.65% eyes and pan retinal photocoagulation in 58.42% eyes. The anatomical success was achieved in 95.5% eyes, visual improvement in 68.54%, static in 14.6% and worsened in 16.86% of eyes. About 15.7% of eyes had some form of post- operative complications.

Conclusions: Vitreous hemorrhage with tractional retinal detachment, persistent vitreous hemorrhage and tractional retinal detachment involving macula were the common indication of pars plana vitrectomy among cases of Proliferative diabetic retinopathy. Anatomical success and visual acuity improvement can be achieved in majority of the eyes following PPV in Proliferative diabetic retinopathy.

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来源期刊

Journal of Nepal Health Research Council Medicine-Medicine (all)

CiteScore

1.40

自引率

0.00%

发文量

审稿时长

15 weeks

期刊介绍： The journal publishes articles related to researches done in the field of biomedical sciences related to all the discipline of the medical sciences, medical education, public health, health care management, including ethical and social issues pertaining to health. The journal gives preference to clinically oriented studies over experimental and animal studies. The Journal would publish peer-reviewed original research papers, case reports, systematic reviews and meta-analysis. Editorial, Guest Editorial, Viewpoint and letter to the editor are solicited by the editorial board. Frequently Asked Questions (FAQ) regarding manuscript submission and processing at JNHRC.