抗寄生虫药物制剂分析

A. Kadyrbai, L.N. Ibragimova, M. B. Ibrayeva, T. Bekezhanova, R.V. Kuzmina, V.V. Kuzmina, A. A. Bakytkhanova, A.A. Satur, Z. B. Sakipova
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摘要

目前,寄生虫病是世界上最普遍的疾病之一。对近年来欧亚经济联盟国家人口流行病情况的统计分析表明,寄生虫病的发病率在不断增加。这种情况表明,有必要分析哈萨克斯坦共和国居民对抗寄生虫药物的满意度,并将哈萨克斯坦国立医药大学药学院科学家在药用植物原料基础上研发的创新药物引入国内生产。目的对哈萨克斯坦境内注册的抗寄生虫药物市场进行分析。材料与方法研究对象是在哈萨克斯坦共和国境内注册的国家药品和医疗器械登记处、"i-teka. kz "数据库和其他医药市场以及 "IQVIA "数据库中的商品名称列表。结果。根据分析结果,抗寄生虫药物在所有注册药物中所占比例仅为1.49%,国内生产仅占10%,由5家哈萨克斯坦制药公司代表。根据 ATC 分类对研究药物进行的分析表明,妇科使用的抗菌药物和消毒剂是一个很大的分组。在所有注册药物中,片剂和栓剂最为常见。药物的成本和疗程差别很大。根据销售分析,阿苯达唑的销量居首位,年销量达 50 万盒。结论。因此,抗寄生虫药物市场主要以进口产品为主。因此,国内制药业最重要的任务之一是确保进口替代,即开发和生产基于国内原材料的抗寄生虫产品。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
ANALYSIS OF PHARMACEUTICAL PREPARATIONS OF ANTIPARASITIC PROFILE
Currently, parasitic diseases are among the most widespread in the world. Statistical analysis of the recent years’ epidemic situation among the population of the Eurasian Economic Union countries has demonstrated a dynamic increase in the incidence of parasitic invasions. This situation indicates the need to analyze the satisfaction of the population of the Republic of Kazakhstan with antiparasitic medicines and to introduce into domestic production new innovative pharmaceutical developments of scientists of S.D. Asfendiyarov KazNMU School of Pharmacy, worked out based medicinal plant raw materials. Purpose. Analysis of the pharmaceutical market of antiparasitic drugs registered in the territory of Kazakhstan. Materials and methods. The object of the study is the list of trade names in the State Register of Medicines and Medical Devices registered in the territory of Kazakhstan, in the “i-teka. kz” database and other pharmacy markets, and the “IQVIA” database. Results. Based on the results of the analysis, it was established that the share of antiparasitic drugs in the context of all registered ones was only 1.49%, with only 10% of domestic production, represented by 5 Kazakh pharmaceutical companies. Analysis of the studied drugs according to the ATC classification showed that a large subgroup includes antimicrobial drugs and antiseptics used in gynecology. Among all registered drugs, tablets and suppositories are the most common. The cost of drugs and their course of treatment varies widely. According to sales analysis, the leader is albendazole, with a sales volume of 500 thousand packs annually. Conclusion. Thus, the market of antiparasitic drugs is represented mainly by imported products. Therefore, one of the most significant tasks of the domestic pharmaceutical industry is to ensure import substitution, which is to develop and create antiparasitic products based on domestic raw materials.
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