N6-甲基腺苷阅读器与神经母细胞瘤之间的相互影响

Clinical and translational discovery Pub Date : 2024-07-23 DOI:10.1002/ctd2.344

Liping Chen, Jing He, Zhenjian Zhuo

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引用次数: 0

摘要

神经母细胞瘤（NB）是一种异质性儿科实体瘤，受表观遗传修饰的影响很大。本综述探讨了N6-甲基腺苷（m6A）修饰及其阅读器在NB进展中的作用。m6A阅读器（包括YTHDF1/2、YTHDC1、IGF2BP1/2/3、HNRNPA2B1和HNRNPC）的失调与NB的易感性和进展有关。了解m6A阅读器与NB之间的相互关系可为诊断、预后和治疗策略提供新的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

The crosstalk between N6-methyladenosine readers and neuroblastoma