慢性丁型肝炎的组织学和免疫组织化学特征。

Basic and applied histochemistry Pub Date : 1988-01-01
C Mariscotti, P Viganò, R Costa, G Gubertini, A Cargnel
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引用次数: 0

摘要

对46例HBsAg δ /抗δ血清阳性的慢性肝炎患者的肝活检标本与HBsAg δ阳性/抗δ阴性患者的肝标本进行比较。结果表明,在Delta系统血清阳性的受试者中,组织学损伤和炎症更为严重。几乎所有Delta IR患者(93.5%)的肝细胞核中均发现特异性病毒抗原。扩散速度与组织学病变的严重程度成正比,这与其他各种研究确定的德尔塔病毒的直接细胞病变作用一致。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Histological and immunohistochemical features in chronic delta hepatitis.

Forty-six liver biopsies from HBsAg Delta/anti-Delta serum positive patients with chronic hepatitis were compared with liver specimens from HBsAg positive Delta/antiDelta negative patients. The results indicate more severe histologic damage and inflammation among subjects who are serum-positive to the Delta system. Specific virus antigen was found in liver cell nuclei of almost all the Delta IR patients (93.5%). The rate of diffusion was directly proportional to the severity of histological lesions, which is in linea with the direct cytopathic effect of the Delta virus as ascertained in various other studies.

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