{"title":"朗格汉斯细胞组织细胞增生症的细胞学诊断。两个病例","authors":"Eleni Thodou, Konstantina Papaharalambous, Eleni Lappa, Irini Skliva, Ekaterini Diamanti, Giannis Kokkinakis, Eleni Konsolaki, Dimitrios Tamiolakis","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Langerhans cell histiocytosis (LCH) comprises a wide spectrum of clinical presentations in children and adults, ranging from favorable lesions to aggressive disseminated disease. We present 2 cases where cytology introduced the diagnosis of LCH in the appropriate clinicoradioliogical settings. Cytology can serve accurately in LCH interpretation based on the characteristic cytomorphology and selected immunocytochemistry, so unwarranted biopsy can be overruled and treatment can be adjusted largely where histopathology services are unavailable. Diagnosis may be difficult in cases with scant or insufficient cellular material.</p>","PeriodicalId":94215,"journal":{"name":"Stomatologija","volume":"25 3","pages":"79-83"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Cytological diagnosis of Langerhans cell histiocytosis. Apropos 2 cases.\",\"authors\":\"Eleni Thodou, Konstantina Papaharalambous, Eleni Lappa, Irini Skliva, Ekaterini Diamanti, Giannis Kokkinakis, Eleni Konsolaki, Dimitrios Tamiolakis\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Langerhans cell histiocytosis (LCH) comprises a wide spectrum of clinical presentations in children and adults, ranging from favorable lesions to aggressive disseminated disease. We present 2 cases where cytology introduced the diagnosis of LCH in the appropriate clinicoradioliogical settings. Cytology can serve accurately in LCH interpretation based on the characteristic cytomorphology and selected immunocytochemistry, so unwarranted biopsy can be overruled and treatment can be adjusted largely where histopathology services are unavailable. Diagnosis may be difficult in cases with scant or insufficient cellular material.</p>\",\"PeriodicalId\":94215,\"journal\":{\"name\":\"Stomatologija\",\"volume\":\"25 3\",\"pages\":\"79-83\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Stomatologija\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Stomatologija","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Cytological diagnosis of Langerhans cell histiocytosis. Apropos 2 cases.
Langerhans cell histiocytosis (LCH) comprises a wide spectrum of clinical presentations in children and adults, ranging from favorable lesions to aggressive disseminated disease. We present 2 cases where cytology introduced the diagnosis of LCH in the appropriate clinicoradioliogical settings. Cytology can serve accurately in LCH interpretation based on the characteristic cytomorphology and selected immunocytochemistry, so unwarranted biopsy can be overruled and treatment can be adjusted largely where histopathology services are unavailable. Diagnosis may be difficult in cases with scant or insufficient cellular material.