铀生物测定的最小可检测摄入量和剂量--阿尔法光谱法与 ICP-MS 的比较。

IF 1 4区医学 Q4 ENVIRONMENTAL SCIENCES

Health physics Pub Date : 2024-07-25 DOI:10.1097/HP.0000000000001854

B Rosenberg, A Johnson, C G Potter, C L Antonio

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引用次数: 0

摘要

摘要：天然存在的铀使职业暴露监测变得复杂。有几种可用于监测职业暴露的追溯方法，每种方法都有优点和缺点。本文比较了质谱法和阿尔法光谱法对尿液中铀的分析，并介绍了确定职业接触的方法。比较了每种分析方法的最低检测浓度，以及根据各种溶解类型和混合物的分析结果确定摄入量的方法。根据拟议的摄入量确定方法计算出的最低检测剂量，发现在检测人为混合物的职业接触方面，带有放射化学分离的质谱法是最灵敏的分析方法。

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Minimum Detectable Intakes and Doses for Uranium Bioassays-Comparison between Alpha Spectrometry and ICP-MS.

Abstract: Naturally occurring uranium complicates monitoring for occupational exposures. There are several retroactive methods that can be used to monitor for occupational exposures, with benefits and drawbacks to each. Analysis of uranium in urine by mass spectrometry and alpha spectrometry is compared, and methods of determining an occupational exposure are presented. The minimum detectable concentrations from each analysis and a method for intake determination based on the analytical results are compared for various solubility types and mixtures. Mass spectrometry with radiochemical separation was found to be the most sensitive analysis for detecting occupational exposures to anthropogenic mixtures based on minimum detectable doses calculated from the proposed method for intake determination.

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来源期刊

Health physics 医学-公共卫生、环境卫生与职业卫生

CiteScore

4.20

自引率

0.00%

发文量

324

审稿时长

3-8 weeks

期刊介绍： Health Physics, first published in 1958, provides the latest research to a wide variety of radiation safety professionals including health physicists, nuclear chemists, medical physicists, and radiation safety officers with interests in nuclear and radiation science. The Journal allows professionals in these and other disciplines in science and engineering to stay on the cutting edge of scientific and technological advances in the field of radiation safety. The Journal publishes original papers, technical notes, articles on advances in practical applications, editorials, and correspondence. Journal articles report on the latest findings in theoretical, practical, and applied disciplines of epidemiology and radiation effects, radiation biology and radiation science, radiation ecology, and related fields.