{"title":"生物论文 8/2024","authors":"","doi":"10.1002/bies.202470012","DOIUrl":null,"url":null,"abstract":"<p>Eukaryotic chromosome ends are characterized by specialized structures, namely telomeres. Telomeric DNA is usually rich in guanines and is able to form four-stranded G-quadruplexes. In article 2300229, So Young Joo et al. review how dynamic interactions between G-quadruplexes and the tumor suppressor BRCA2 influence telomere replication.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure>\n </p>","PeriodicalId":9264,"journal":{"name":"BioEssays","volume":"46 8","pages":""},"PeriodicalIF":3.2000,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bies.202470012","citationCount":"0","resultStr":"{\"title\":\"BioEssays 8/2024\",\"authors\":\"\",\"doi\":\"10.1002/bies.202470012\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Eukaryotic chromosome ends are characterized by specialized structures, namely telomeres. Telomeric DNA is usually rich in guanines and is able to form four-stranded G-quadruplexes. In article 2300229, So Young Joo et al. review how dynamic interactions between G-quadruplexes and the tumor suppressor BRCA2 influence telomere replication.\\n\\n <figure>\\n <div><picture>\\n <source></source></picture><p></p>\\n </div>\\n </figure>\\n </p>\",\"PeriodicalId\":9264,\"journal\":{\"name\":\"BioEssays\",\"volume\":\"46 8\",\"pages\":\"\"},\"PeriodicalIF\":3.2000,\"publicationDate\":\"2024-07-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bies.202470012\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BioEssays\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/bies.202470012\",\"RegionNum\":3,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BioEssays","FirstCategoryId":"99","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/bies.202470012","RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
真核生物染色体末端具有特殊的结构,即端粒。端粒 DNA 通常富含鸟嘌呤,能够形成四链 G-四联体。在第 2300229 号文章中,So Young Joo 等人回顾了 G-四叠体与肿瘤抑制因子 BRCA2 之间的动态相互作用如何影响端粒复制。
Eukaryotic chromosome ends are characterized by specialized structures, namely telomeres. Telomeric DNA is usually rich in guanines and is able to form four-stranded G-quadruplexes. In article 2300229, So Young Joo et al. review how dynamic interactions between G-quadruplexes and the tumor suppressor BRCA2 influence telomere replication.
期刊介绍:
molecular – cellular – biomedical – physiology – translational research – systems - hypotheses encouraged
BioEssays is a peer-reviewed, review-and-discussion journal. Our aims are to publish novel insights, forward-looking reviews and commentaries in contemporary biology with a molecular, genetic, cellular, or physiological dimension, and serve as a discussion forum for new ideas in these areas. An additional goal is to encourage transdisciplinarity and integrative biology in the context of organismal studies, systems approaches, through to ecosystems, where appropriate.