治疗痛风的当前挑战和新兴疗法。

IF 1.2 Q4 RHEUMATOLOGY

Current rheumatology reviews Pub Date : 2024-07-22 DOI:10.2174/0115733971302054240627072809

Shanthini Sivaprakasam, Jawahar Natarajan, Jigyasa Singh, Monisha Rajesh

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引用次数: 0

摘要

痛风是一种常见的炎症性关节炎，其特点是 MSU 沉积在关节和周围组织中，导致炎症和反复发作的疼痛。目前，黄嘌呤氧化酶抑制剂（即别嘌醇和非布索坦）被用于治疗痛风。最近，含有金属氧化物和非金属氧化物的纳米粒子（NPs）也被开发出来，以更好地控制痛风。本综述概述了痛风的病理生理学、目前用于治疗痛风的药物以及新出现的痛风疗法。

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Current Challenges and Emerging Therapies in the Treatment of Gout.

Gout is a common form of inflammatory arthritis characterized by the deposition of MSU in the joints and surrounding tissues, which results in inflammation and recurrent painful attacks. Currently, xanthine oxidase inhibitors, i.e., Allopurinol and Febuxostat, are used in the therapy. Recently, nanoparticles (NPs) containing metal oxides and non-metal oxides have also been developed to better manage gout. This comprehensive review summarizes the pathophysiology of gout, currently used drugs in the treatment, followed by emerging therapies for gout.

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来源期刊

Current rheumatology reviews RHEUMATOLOGY-

CiteScore

2.30

自引率

0.00%

发文量

期刊介绍： Current Rheumatology Reviews publishes frontier reviews on all the latest advances on rheumatology and its related areas e.g. pharmacology, pathogenesis, epidemiology, clinical care, and therapy. The journal"s aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians in rheumatology.