解码和破解 Mpox、疱疹和梅毒感染:最新技术回顾。

IF 2.2 4区 医学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Jiao Wang, Rajat Goyal, Rupesh K Gautam, Kajal Garg, Shaheen Husain, Hitesh Chopra, Ankit Kumar Dubey, Rehab A Rayan, Mohammad Amjad Kamal, Dinesh Kumar Mishra, Rohit Gundamaraju, Bairong Shen, Rajeev K Singla
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引用次数: 0

摘要

随着全球从 COVID-19 大流行中恢复过来,MPXV 病例的再次出现引起了人们的严重关切。MPXV 早期的临床表现与流感和感冒等常见疾病相似,而且其不断发展的皮疹也与其他感染相似,这突出了及时准确诊断的重要性。在这些感染中,天花在临床上与 MPXV 最为相似,梅毒和水痘带状疱疹也会出现与 MPXV 阶段相似的皮疹。我们对 MPXV、疱疹和梅毒进行了全面回顾,包括结构和形态特征、起源、传播方式和计算研究。使用MeSH关键术语在PubMed上搜索MPXV的文献,共获得1904条结果,分析结果显示MPXV与性传播疾病有显著联系。对 MPXV、单纯疱疹病毒(HSV)和梅毒的更深入探讨进一步揭示了疾病之间的相互联系和地域相关性。这些发现强调了全面了解这些相互关联的传染病病原体的必要性,以便更好地进行控制和管理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Decoding and Unravelling Mpox, Herpes, and Syphilis Infections: A State of Art Review.

As the world recovers from the COVID-19 pandemic, a resurgence in MPXV cases is causing serious concern. The early clinical similarity of MPXV to common ailments like the flu and cold, coupled with the resemblances of its progressing rash to other infections, underscores the importance of prompt and accurate diagnosis. Among the infections, smallpox is clinically closest to MPXV, and rashes similar to MPXV stages also appear in syphilis and varicella zoster. A comprehensive review of MPXV, herpes, and syphilis was carried out, including structural and morphological features, origins, transmission modes, and computational studies. PubMed literature search on MPXV, using MeSH key terms, yielded 1904 results, with the analysis revealing prominent links to sexually transmitted diseases. More in-depth exploration of MPXV, Herpes Simplex Virus (HSV), and Syphilis revealed further disease interconnections and geographical correlations. These findings emphasize the need for a holistic understanding of these interconnected infectious agents for better control and management.

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来源期刊
Current pharmaceutical biotechnology
Current pharmaceutical biotechnology 医学-生化与分子生物学
CiteScore
5.60
自引率
3.60%
发文量
203
审稿时长
6 months
期刊介绍: Current Pharmaceutical Biotechnology aims to cover all the latest and outstanding developments in Pharmaceutical Biotechnology. Each issue of the journal includes timely in-depth reviews, original research articles and letters written by leaders in the field, covering a range of current topics in scientific areas of Pharmaceutical Biotechnology. Invited and unsolicited review articles are welcome. The journal encourages contributions describing research at the interface of drug discovery and pharmacological applications, involving in vitro investigations and pre-clinical or clinical studies. Scientific areas within the scope of the journal include pharmaceutical chemistry, biochemistry and genetics, molecular and cellular biology, and polymer and materials sciences as they relate to pharmaceutical science and biotechnology. In addition, the journal also considers comprehensive studies and research advances pertaining food chemistry with pharmaceutical implication. Areas of interest include: DNA/protein engineering and processing Synthetic biotechnology Omics (genomics, proteomics, metabolomics and systems biology) Therapeutic biotechnology (gene therapy, peptide inhibitors, enzymes) Drug delivery and targeting Nanobiotechnology Molecular pharmaceutics and molecular pharmacology Analytical biotechnology (biosensing, advanced technology for detection of bioanalytes) Pharmacokinetics and pharmacodynamics Applied Microbiology Bioinformatics (computational biopharmaceutics and modeling) Environmental biotechnology Regenerative medicine (stem cells, tissue engineering and biomaterials) Translational immunology (cell therapies, antibody engineering, xenotransplantation) Industrial bioprocesses for drug production and development Biosafety Biotech ethics Special Issues devoted to crucial topics, providing the latest comprehensive information on cutting-edge areas of research and technological advances, are welcome. Current Pharmaceutical Biotechnology is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments.
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