立即变色反应。

Photo-dermatology Pub Date : 1988-04-01
H Beitner
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引用次数: 0

摘要

直接色素变黑反应(IPD)是一种主要由长波紫外线(UVA)辐射引起的皮肤灰褐色变色。IPD的阈值可以作为一系列光测试的重要参数。该反应的主要机制是引起预形成黑色素变暗和自由基产生的光氧化过程。也有人认为,该反应涉及黑素细胞的微形态学改变和角化细胞中黑素小体分布模式的改变。这一概念最近受到独立调查人员的质疑。IPD的生理功能在很大程度上仍然未知。未观察到该反应的光保护作用。有人认为,IPD可能在人类进化过程中有价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Immediate pigment-darkening reaction.

The immediate pigment-darkening reaction (IPD) is a gray-brown discoloration of the skin induced mainly by long-wave ultraviolet (UVA) radiation. The threshold value of IPD can be used as an important parameter in a series of light tests. The principle mechanism of the reaction is a photo-oxidative process causing darkening of preformed melanin and the production of free radicals. It has also been suggested that the reaction involves micromorphological changes in the melanocytes and a changed distribution pattern of melanosomes in the keratinocytes. This concept has recently been questioned by independent investigators. The physiological function of IPD still remains largely unknown. No photoprotective effect of the reaction has been observed. It has been suggested that IPD might have been of value during human evolution.

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