通过离子液体支撑的 Cu(II) 催化剂以可持续的方式微波辅助合成 2-(het)/芳基喹唑啉-4(3H)-酮

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-07-15 DOI:10.1016/j.tetlet.2024.155182

Md Gulzar Ahmad , Balamurali MM , Kaushik Chanda

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引用次数: 0

摘要

通过使用可重复使用的咪唑基离子液体支撑铜（II）催化剂，介绍了一种从取代的 2- 氨基苯甲酰胺和苄醇微波辅助合成 2-（het）/芳基喹唑啉-4（3H）-酮的高效且可持续的方法。这种方法对官能团的耐受性很高，并能高效地构建出所需的产品，产量从良好到极佳。此外，与已报道的方案相比，该方法操作简单，反应时间短，成本最低，具有可持续性。此外，该催化剂可回收和重复使用达 4 个连续周期，且活性不会明显降低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

A sustainable approach to microwave assisted synthesis of 2-(het)/arylquinazolin-4(3H)-ones via ionic liquid supported Cu(II) catalyst

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A sustainable approach to microwave assisted synthesis of 2-(het)/arylquinazolin-4(3H)-ones via ionic liquid supported Cu(II) catalyst

An efficient and sustainable approach for the microwave assisted synthesis of 2-(het)/arylquinazolin-4(3H)-ones from substituted 2-aminobenzamide and benzyl alcohols is introduced by using a reusable imidazolium based ionic liquid supported Cu(II) catalyst. This methodology exhibits high functional group tolerance and efficiently constructs desired products in good to excellent yields. Moreover, this method portrays operational simplicity, less reaction time, minimal cost and sustainable over the reported protocols. Furthermore, the catalyst can be recycled and reused up to 4 consecutive cycles with no significant loss of activity.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.