创伤后应激障碍的神经分子分析--神经元和信号通路的失调

Q4 Biochemistry, Genetics and Molecular Biology

Medical Journal of Cell Biology Pub Date : 2024-07-01 DOI:10.2478/acb-2024-0003

Livhuwani Nesengani, Vanessa Andrine Sherington, Chloe Snaifer

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引用次数: 0

摘要

摘要创伤后应激障碍（PTSD）是一种因生命受到威胁而导致的精神障碍，进而影响日常生活质量。这归因于对大脑功能构成产生负面影响的大量神经分子因素。这些因素之间复杂的相互作用包括神经元的改变和神经可塑性、信号分子、星形胶质细胞和胶质细胞的改变，它们共同作用于多个脑区的生存机制。

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Neuromolecular analysis of post-traumatic stress disorder – the dysregulation in neuronal and signalling pathways

Abstract Post-traumatic stress disorder (PTSD) is a mental disorder as a result of life-threatening situations which in turn affects quality of life through activities of daily living. This is attributed to a plethora of neuromolecular factors negatively affecting the functional make-up of the brain. The complex interplay of these factors include neuronal alterations and neuroplasticity, signalling molecular, astrocyte and glial cell alterations which together act as a survival mechanism in several brain regions.

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来源期刊

Medical Journal of Cell Biology Biochemistry, Genetics and Molecular Biology-Cell Biology

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