精油在癌症治疗中的治疗潜力:全面回顾

Howard Lopes Ribeiro Júnior
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引用次数: 0

摘要

精油以其复杂的生物活性化合物混合物而闻名,长期以来一直被用于传统医学,并显示出治疗包括癌症在内的各种疾病的潜力。最近的研究强调了它们的抗癌特性,如细胞毒性、抗增殖和抗转移作用。精油中含有萜烯和苯丙酮类等分子,可通过干扰细胞信号传导途径诱导癌细胞凋亡。例如,乳香精油能诱导乳腺癌细胞的程序性细胞死亡,而姜黄素和百里酚等化合物则能抑制结直肠癌细胞的增殖。此外,某些精油还能通过抑制癌细胞的迁移和入侵来防止癌细胞转移。尽管临床前研究结果令人鼓舞,但精油治疗癌症的有效性和安全性还需要通过人体临床试验来进一步验证。这篇综述讨论了精油作为辅助疗法在癌症治疗中的潜力,强调由于精油的浓缩性质和可能的不良反应,需要在专业人士的指导下谨慎使用。精油的治疗前景在于其诱导细胞凋亡、抑制细胞增殖和防止转移的能力,这强调了严格研究的重要性,以确保在肿瘤学中安全有效地使用精油。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Therapeutic Potential of Essential Oils in Cancer Treatment: A Comprehensive Review
Essential oils, known for their complex mixture of bioactive compounds, have long been used in traditional medicine and have shown potential in treating various diseases, including cancer. Recent studies highlight their anticancer properties, such as cytotoxic, antiproliferative, and antimetastatic effects. Essential oils contain molecules like terpenes and phenylpropanoids, which induce apoptosis in cancer cells by interfering with cellular signaling pathways. For instance, frankincense oil induces programmed cell death in breast cancer cells, while compounds like curcumin and thymol inhibit the proliferation of colorectal cancer cells. Additionally, certain essential oils prevent metastasis by inhibiting the migration and invasion of cancer cells. Despite promising preclinical results, the effectiveness and safety of essential oils in cancer treatment require further validation through human clinical trials. This review discusses the potential of essential oils as complementary therapies in cancer treatment, emphasizing the need for cautious application under professional supervision due to their concentrated nature and possible adverse effects. The therapeutic promise of essential oils lies in their ability to induce apoptosis, inhibit cell proliferation, and prevent metastasis, underscoring the importance of rigorous research to ensure their safe and effective use in oncology.
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