{"title":"商业分子测定法漏检的利福平和异烟肼抗药性","authors":"L. Richards, F. Ismail, J. Nel, S. V. Omar","doi":"10.7196/samj.2024.v114i17.1779","DOIUrl":null,"url":null,"abstract":"\n\n\n\nDrug-resistant tuberculosis (TB) has poor outcomes unless resistance is detected early, ideally by commercially available molecular tests. We present a case of occult multidrug-resistant TB where both rifampicin and isoniazid resistance were missed by molecular testing and were only identified by phenotypic testing.\n\n\n\n","PeriodicalId":22034,"journal":{"name":"South African Medical Journal","volume":"11 8","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Missed rifampicin and isoniazid resistance by commercial molecular assays\",\"authors\":\"L. Richards, F. Ismail, J. Nel, S. V. Omar\",\"doi\":\"10.7196/samj.2024.v114i17.1779\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\n\\n\\n\\nDrug-resistant tuberculosis (TB) has poor outcomes unless resistance is detected early, ideally by commercially available molecular tests. We present a case of occult multidrug-resistant TB where both rifampicin and isoniazid resistance were missed by molecular testing and were only identified by phenotypic testing.\\n\\n\\n\\n\",\"PeriodicalId\":22034,\"journal\":{\"name\":\"South African Medical Journal\",\"volume\":\"11 8\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"South African Medical Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.7196/samj.2024.v114i17.1779\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"South African Medical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7196/samj.2024.v114i17.1779","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Missed rifampicin and isoniazid resistance by commercial molecular assays
Drug-resistant tuberculosis (TB) has poor outcomes unless resistance is detected early, ideally by commercially available molecular tests. We present a case of occult multidrug-resistant TB where both rifampicin and isoniazid resistance were missed by molecular testing and were only identified by phenotypic testing.
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