腔肺分流术后左侧改良型BLALOCK-TAUSSIG分流术的中长期评估:回顾性队列研究

Ahmed Rady Attallah, Shady E. M. Elwany, Khaled M. Samer, Radwa M. A. Abozed, Mohamed Adel
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摘要

.摘要 背景:先天性心脏病是最常见的先天性畸形。有些先天性心脏病在婴儿出生后的最初几天或几年内可能并不引人注意,但其他先天性心脏病则相当严重,会危及生命,因为其主要畸形会导致含氧和脱氧血液混合。这些病例大多无法修复,需要分离静脉血和动脉血,以帮助提高血氧饱和度(SpO 2)。研究目的:本研究旨在评估双向腔肺分流术后左侧改良鲍洛克-陶西格(MBT)分流术的中长期效果。患者和方法:对 20 名在双向格伦手术后接受 MBTS 的患者进行了回顾性队列研究。我们评估了 MBTS 对这些患者的中长期影响,尤其是 SpO 2 和超声心动图结果。该研究考虑了赫尔辛基宣言的伦理原则,并获得了本机构研究伦理委员会的批准(MS 510/2023)。结果术后 SpO 2 与术前 SpO 2 相比有明显增加(P<0.001),平均差为 20.95%。结论:先天性紫绀型心脏病是一种危及生命的疾病,主要问题是动静脉血液混合导致的血氧饱和度降低。双向格伦是分离含氧和脱氧血液的一个步骤。但随后 SpO 2 会继续下降,需要进一步干预。在这项研究中,我们发现 MBTS 可使大量不适合接受其他手术的患者术后 SpO 2 显著增加,且无明显并发症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mid and long-term evaluation of left modified blalock-taussig shunt after cavopulmonary shunts: A retrospective cohort study
. ABSTRACT Background: Congenital heart diseases are the most common type of congenital malformations. Some of them may pass unnoticeable in the first days or maybe years of life, but the others are pretty serious and life-threatening due to major malformations that lead to the mixing of oxygenated and deoxygenated blood. Most of these cases are not repairable and require separating the venous and arterial blood to help improve oxygen saturation (SpO 2 ). Aim: The study aims to evaluate the mid and long-term effects of left modified blalock-taussig (MBT) shunt after bidirectional cavopulmonary shunt. Patients and Methods: A retrospective cohort study was conducted on 20 patients who underwent MBTS after Bidirectional Glenn. We evaluated the mid and long-term effects of MBTS in those patients, especially SpO 2 and echocardiographic findings. The study considered the ethical principles of the Helsinki Declaration approval from the research ethics committee at our institution (MS 510/2023). Results: There was a significant increase in postoperative SpO 2 in comparison to preoperative SpO 2 ( P<0.001 ) with a mean difference of 20.95%. Conclusion: Congenital cyanotic heart disease represents a life-threatening condition where the main problem is desaturation due to the mixing of arterial and venous blood. Bidirectional Glenn is a step to separate the oxygenated and deoxygenated blood. But later on, SpO 2 continues to decline and further intervention is needed. In this study, we found that MBTS provides a postoperative significant increase in SpO 2 in a wide group of those patients even who are not candidates for other operations without significant complications.
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