Comparative evaluation of efficacy of Kulattha Gutika with Atorvastatin in the management of Dyslipidemia (Medoroga) - RCT

Introduction: Dyslipidemia is the disorder of lipoprotein metabolism manifested by an elevation of the total cholesterol, the low-density lipoprotein (LDL) cholesterol, the triglyceride concentrations, and a decrease in the high-density lipoprotein (HDL) cholesterol concentration in the blood. Today’s unhealthy food habits and sedentary lifestyle are the main causative factors for Dyslipidemia. It is not defined in Ayurveda, it can be related to a number of conditions, including "Medoroga, Rasa Raktagata Snehavruddhi Shonitabhishyandana, and Dhamanipratichaya" based on similarities in etiology, pathogenesis, and manifestations. Aim: Comparative evaluation of Efficacy of Kulattha Gutika and Atorvastatin in the Management of Dyslipidemia (Medoroga). Material and Methods: Study comprises total 60 patients of Dyslipidemia randomly divided into two equal groups. Group A (Experimental group) was treated with 1gm Kulattha Gutika thrice a day before meals with warm water and Group B (Control group) was treated with 10 mg Atorvastatin at night before sleep with water for 45 days. Patients were assessed for Objective parameters like Lipid profile (S. TCH, TG, LDL, HDL, VLDL) and BMI was done on 0 and 45th day. Result: Statistically significant improvement was observed in objective parameters like TCH, HDL, LDL, VLDL, and TG in both groups. But in BMI Statistically significant improvement was observed in group A, treated with Kulattha Gutika. Conclusion: Kulattha Gutika is as efficacious as Atorvastatin in managing Dyslipidemia (Medoroga) and is an economical alternative without adverse effects.