唾液生物标志物--牙周病学的新时代

N. Thomas, Kavya S, Thomas George V
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摘要

牙周炎是一种慢性炎症性非传染性疾病,会影响牙周的各个部位,造成不可逆转的损害。致病或正常过程的生物标志称为生物标志物。寻找生物标志物有助于跟踪病理状况的发展,也有助于疾病的预防、诊断和预后。有效的治疗在很大程度上取决于疾病的早期识别。及早发现和治疗可减轻疾病过程的严重程度和潜在影响。在牙周病学领域,传统的临床标准往往不足以确定活动性疾病的部位、跟踪治疗效果或衡量未来的易感程度。为了克服这一障碍,医学研究人员致力于确定分子疾病生物标志物,这些标志物能在疾病变得复杂之前显示出隐藏的致命威胁。唾液是一种重要的生理液体,含有复杂的化学混合物。作为一种诊断工具,它正变得越来越受欢迎。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Salivary biomarkers – Emerging era in periodontics
Periodontitis is a chronic inflammatory noncommunicable disease that affects all parts of the periodontium and causes irreversible damage. A biological sign of either pathogenic or normal processes is called a biomarker. Finding biomarkers is helpful for tracking the advancement of pathological conditions as well as for disease prevention, diagnosis, and prognosis. Effective treatment depends heavily on early disease identification. The disease process's severity and potential implications are lessened by early detection and treatment. Traditional clinical criteria are frequently inadequate in the field of periodontology to identify sites of active disease, track the effectiveness of therapy, or gauge the degree of vulnerability to future. Medical researchers are committed to identifying molecular illness biomarkers that indicate a concealed deadly threat prior to the disease becoming complicated in order to overcome this obstacle. Saliva is a vital physiological fluid that contains a complex mixture of chemicals. As a diagnostic tool, it is becoming more and more popular.
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