{"title":"包皮环切术后 HIV 阴性中年患者的原发性典型阴茎卡波西肉瘤：一个罕见病例的介绍","authors":"Rifat Burak Ergul, Mazhar Ortac, Senol Tonyali, Gizem Pehlivan, Sule Ozturk Sari, Ozge Hurdogan, Ates Kadioglu","doi":"10.14744/SEMB.2023.46034","DOIUrl":null,"url":null,"abstract":"<p><p>Kaposi's sarcoma should be considered in the differential diagnosis in young patients with penile lesions and no risk factors. A 37-year-old heterosexual man with no other medical history applied presented with a non-itchy and painless penile lesion, for three months. The HIV 1-2 serology was negative via ELISA test. Histopathological analysis of the lesion revealed a tumor composed of atypical spindle cells, below a partially ulcerated surface. There was also an abundance of plasma cells admixed within the neoplastic cells. The patient was diagnosed as HIV-negative, HHV-8 positive Kaposi sarcoma. Although penile Kaposi sarcoma is extremely rare, classical Kaposi sarcoma should be considered in the differential diagnosis of penile lesions.</p>","PeriodicalId":42218,"journal":{"name":"Medical Bulletin of Sisli Etfal Hospital","volume":null,"pages":null},"PeriodicalIF":1.0000,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11249993/pdf/","citationCount":"0","resultStr":"{\"title\":\"Primary Classic Penile Kaposi's Sarcoma in a Middle Age Circumcised HIV-Negative Patient: Presentation of an Unusual Case.\",\"authors\":\"Rifat Burak Ergul, Mazhar Ortac, Senol Tonyali, Gizem Pehlivan, Sule Ozturk Sari, Ozge Hurdogan, Ates Kadioglu\",\"doi\":\"10.14744/SEMB.2023.46034\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Kaposi's sarcoma should be considered in the differential diagnosis in young patients with penile lesions and no risk factors. A 37-year-old heterosexual man with no other medical history applied presented with a non-itchy and painless penile lesion, for three months. The HIV 1-2 serology was negative via ELISA test. Histopathological analysis of the lesion revealed a tumor composed of atypical spindle cells, below a partially ulcerated surface. There was also an abundance of plasma cells admixed within the neoplastic cells. The patient was diagnosed as HIV-negative, HHV-8 positive Kaposi sarcoma. Although penile Kaposi sarcoma is extremely rare, classical Kaposi sarcoma should be considered in the differential diagnosis of penile lesions.</p>\",\"PeriodicalId\":42218,\"journal\":{\"name\":\"Medical Bulletin of Sisli Etfal Hospital\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2024-06-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11249993/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medical Bulletin of Sisli Etfal Hospital\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.14744/SEMB.2023.46034\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Bulletin of Sisli Etfal Hospital","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14744/SEMB.2023.46034","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
摘要
对于阴茎病变且无危险因素的年轻患者，在鉴别诊断时应考虑卡波西肉瘤。一名无其他病史的 37 岁异性恋男子因阴茎病变而就诊，病变不痛不痒，已持续三个月。经 ELISA 检测，HIV 1-2 血清学检测结果为阴性。病变组织病理学分析显示，肿瘤由非典型纺锤形细胞组成，表面部分溃烂。肿瘤细胞中还混有大量浆细胞。患者被诊断为 HIV 阴性、HHV-8 阳性的卡波西肉瘤。虽然阴茎卡波西肉瘤极为罕见，但在阴茎病变的鉴别诊断中应考虑典型的卡波西肉瘤。
Primary Classic Penile Kaposi's Sarcoma in a Middle Age Circumcised HIV-Negative Patient: Presentation of an Unusual Case.
Kaposi's sarcoma should be considered in the differential diagnosis in young patients with penile lesions and no risk factors. A 37-year-old heterosexual man with no other medical history applied presented with a non-itchy and painless penile lesion, for three months. The HIV 1-2 serology was negative via ELISA test. Histopathological analysis of the lesion revealed a tumor composed of atypical spindle cells, below a partially ulcerated surface. There was also an abundance of plasma cells admixed within the neoplastic cells. The patient was diagnosed as HIV-negative, HHV-8 positive Kaposi sarcoma. Although penile Kaposi sarcoma is extremely rare, classical Kaposi sarcoma should be considered in the differential diagnosis of penile lesions.
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