[哥伦比亚波哥大圣伊格纳西奥大学医院使用腔内功能探头(EndoFLIP)的经验]。

Q4 Medicine
Albis Hani, Valentina Ursida, Raúl Cañadas, Carlos Lombo, María Del Carmen Figueredo, Socorro Moreno Luna
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引用次数: 0

摘要

简介EndoFLIP(英文缩写为:endoluminal functional luminal probe)是一种基于阻抗平面测量原理的系统,可实时测量胃食管交界处的顺应性指数和继发性食管蠕动。虽然这项技术相对较新,其诊断作用仍在评估中,但其在临床实践中的应用已得到越来越多的认可,尤其是在那些食管运动病变(主要是食管胃交界处流出道梗阻和贲门失弛缓症)的压力测定诊断不明确的患者中:本研究旨在介绍哥伦比亚波哥大圣伊格纳西奥大学医院使用 EndoFLIP 的经验:描述性观察病例系列研究,包括2021年至2022年期间在圣伊格纳西奥大学医院接受EndoFLIP治疗的18岁以上患者,包括院内或门诊患者,明确说明研究的执行情况,之前已在多学科消化内科委员会进行过讨论:共有 27 名平均年龄 55 岁的患者参与研究,其中女性 20 人(占 74%),男性 7 人(占 26%)。最常见的研究指征是根据芝加哥 4.0 标准进行的高分辨率食管测压中发现的流出道梗阻诊断不明确(14 名患者),其次是食管收缩过度(4 名患者)和食管运动无效(3 名患者)。在评估收缩反应时发现,9 名流出道梗阻诊断不明确的患者反应正常,3 名无反应,1 名有反应;在贲门失弛缓症诊断不明确的患者中,1 名有边缘收缩反应,2 名无反应。所有既往诊断为无收缩功能的患者在 EndoFLIP 中同样无收缩反应:结论:腔内功能成像技术可评估胃食管交界处、幽门和肛门等括约肌区域的生物力学特性,如扩张性、容积、压力甚至直径。该技术在多个适应症中的作用已得到强调,其中最重要的是对贲门失弛缓症和流出道梗阻等食管运动障碍的不确定诊断,这些病症对患者的生活质量有重大影响,其诊断对于提供最佳治疗方案至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Experience with endoluminal functional luminal probe (EndoFLIP) at San Ignacio University Hospital, Bogota, Colombia].

Introduction: The EndoFLIP (for its acronym in English: endoluminal functional luminal probe) is a system that measures in real time the compliance index of the gastroesophageal junction and secondary esophageal peristalsis, based on the principle of impedance planimetry. Although this technology is relatively new and its diagnostic usefulness is still being evaluated, its use in clinical practice is increasingly recognized, fundamentally in those patients where there is no conclusive manometric diagnosis of esophageal motor pathology, mainly esophagogastric junction outflow obstruction and achalasia.

Objective: The aim of the present study is to describe the experience with EndoFLIP at the San Ignacio University Hospital in Bogotá, Colombia.

Material and methods: Descriptive observational case series study, which included patients over 18 years of age who had undergone EndoFLIP at the San Ignacio University Hospital from 2021 to 2022, either in-hospital or outpatient, with a clear indication of performance of the study, previously discussed in the multidisciplinary Gastroenterology Board.

Results: A total of 27 patients with an average age of 55 years were included in the study, of which 20 were women (74%) and 7 men (26%). The most frequent indication of the study was an inconclusive diagnosis of outflow tract obstruction identified in high-resolution esophageal manometry according to Chicago 4.0 criteria (14 patients), followed by hypercontractile esophagus (4 patients) and ineffective esophageal motility (3 patients). When evaluating the contractile response, it was found that 9 patients with an inconclusive diagnosis of outflow tract obstruction had a normal response, 3 absent and one altered; and in the patients with an inconclusive diagnosis of achalasia, one of them had a borderline contractile response and two had no response. All patients with a previous diagnosis of absent contractility had an equally absent contractile response in EndoFLIP.

Conclusion: Endoluminal functional luminal imaging is a technique that evaluates biomechanical properties such as distensibility, volume, pressure and even diameters of sphincter regions such as the gastroesophageal junction, pylorus and anus. Its usefulness has been highlighted for several indications, the most important being manometrically inconclusive diagnoses of esophageal motor disorders such as achalasia and outflow tract obstruction, pathologies that have a significant impact on the quality of life of patients and whose diagnosis is essential to be able to provide the best treatment option.

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来源期刊
CiteScore
0.40
自引率
0.00%
发文量
49
期刊介绍: La REVISTA DE GASTROENTEROLOGíA DEL PERÚ, es la publicación oficial de la Sociedad de Gastroenterología del Perú que publica artículos originales, artículos de revisión, reporte de casos, cartas e información general de la especialidad; dirigido a los profesionales de la salud con especial interés en la gastroenterología. La Revista de Gastroenterología del Perú es una publicación de periodicidad trimestral y tiene como objetivo la publicación de artículos científicos inéditos en el campo de la gastroenterología, proporcionando información actualizada y relevante de la especialidad y áreas afines. La Revista de Gastroenterología del Perú publica artículos en dos idiomas, español e inglés, a texto completo en la versión impresa yelectrónica. Los artículos científicos son sometidos a revisores o árbitros nacionales e internacionales, especialistas que opinan bajo la modalidad de doble ciego y de manera anónima sobre la calidad y validez de los mismos. El número de revisores depende del tipo de artículo, dos revisores como mínimo para artículos originales y uno como mínimo para otros tipos de artículos.
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