囊性纤维化骨病的特征。

IF 2.6 4区医学 Q1 MEDICINE, GENERAL & INTERNAL

Medicina Clinica Pub Date : 2025-01-10 Epub Date: 2024-07-16 DOI:10.1016/j.medcli.2024.05.014

Victoria Contreras-Bolívar, María Carmen Andreo-López, Manuel Muñoz-Torres

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引用次数: 0

摘要

随着囊性纤维化（CF）患者预期寿命的延长，临床关注的焦点集中在非肺合并症的预防和治疗上。CF相关骨病（CFBD）是一种常见的并发症，会导致骨折率增加。双能 X 射线吸收测量法（DXA）是确定和监测骨骼健康状况的推荐和金标准技术。然而，DXA 因其二维性质而存在局限性。目前已有一些补充 DXA 的工具，如骨小梁评分（TBS）和椎体骨折评估（VFA）。定量计算机断层扫描（QCT）、磁共振成像（MRI）和定量超声波（QUS）也可能有用。

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Characterization of bone disease in cystic fibrosis.

With the increased life expectancy of people with cystic fibrosis (CF), clinical attention has focused on prevention and treatment of non-pulmonary comorbidities. CF-related bone disease (CFBD) is a common complication and leads to increased fracture rates. Dual energy X-ray absorptiometry (DXA) is the recommended and gold standard technique to identify and monitor bone health. However, DXA has limitations because of its two-dimensional nature. Complementary tools to DXA are available, such as trabecular bone score (TBS) and vertebral fracture assessment (VFA). Quantitative computed tomography (QCT), magnetic resonance imaging (MRI) and quantitative ultrasound (QUS) may also be useful.

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来源期刊

Medicina Clinica 医学-医学：内科

CiteScore

3.10

自引率

5.10%

发文量

295

审稿时长

22 days

期刊介绍： Medicina Clínica, fundada en 1943, es una publicación quincenal dedicada a la promoción de la investigación y de la práctica clínica entre los especialistas de la medicina interna, así como otras especialidades. Son características fundamentales de esta publicación el rigor científico y metodológico de sus artículos, la actualidad de los temas y, sobre todo, su sentido práctico, buscando siempre que la información sea de la mayor utilidad en la práctica clínica.