胸腰椎脊髓损伤:管理、技术、时机。

IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE
Marko Jug, Radko Komadina, Klaus Wendt, Hans Christoph Pape, Frank Bloemers, Christoph Nau
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引用次数: 0

摘要

急性创伤性脊髓损伤(tSCI)是一种复杂的异质性损伤,损伤程度、损伤严重性、脊髓受压时间和程度以及血压管理似乎都会影响神经功能的预后。虽然文献中关于胸椎和胸腰椎 tSCI 患者手术减压和脊柱固定效果的数据似乎并不一致,但一些单中心研究表明,早期手术减压可能会带来更好的神经功能预后,尤其是对于不完全 tSCI 患者,因此建议尽快进行手术减压。然而,高能量损伤,尤其是胸腔上层的高能量损伤可能过于严重,手术减压可能无法对其产生影响,而手术减压可能是多发性创伤患者关键的第二次打击。因此,外科医生首先需要严格评估每位患者神经功能恢复的可能性,然后再确定理想的手术时机。手术干预前必须实现循环稳定,并应首选微创手术。入院时就应开始有创血压监测,建议在 5-7 天内将血压维持在 85 至 90 mmHg 之间,并特别注意预防缺氧、发热、酸中毒和深静脉血栓形成。24 小时输注大剂量 MPSS 的作用仍存在争议,但作为一种治疗选择,尤其是在极早期减压或不完全 tSCI 的情况下,治疗外科医生可酌情在急性 tSCI 8 小时内为成人患者提供这种治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Thoracolumbar spinal cord injury: management, techniques, timing.

Thoracolumbar spinal cord injury: management, techniques, timing.

Acute traumatic spinal cord injury (tSCI) is a complex and heterogeneous injury, where the level of injury, injury severity, duration and degree of spinal cord compression, and blood pressure management seem to influence neurologic outcome. Although data in the literature seem to be inconsistent regarding the effectiveness of surgical decompression and spinal fixation in patients with thoracic and thoracolumbar tSCI, some single-center studies suggest that early surgical decompression may lead to a superior neurologic outcome, especially in patients with incomplete tSCI, suggesting surgical decompression to be performed as soon as possible. However, high energy injuries, especially to the upper thoracic levels, may be too severe to be influenced by surgical decompression, which may represent a critical second hit for the polytraumatized patient. Therefore, the surgeon first needs to critically evaluate the potential for neurologic recovery in each patient before determining the ideal timing of surgery. Circulatory stabilization must be achieved before surgical intervention, and minimally invasive procedures should be preferred. Invasive blood pressure monitoring should be started on admission, and maintenance of a MAP between 85 and 90 mmHg is recommended for a duration of 5-7 days, with special attention to the prevention of hypoxia, fever, acidosis and deep venous thrombosis. The role of a 24-hour infusion of high-dose MPSS is still controversial, but it may be offered at the discretion of the treating surgeon to adult patients within 8 h of acute tSCI as a treatment option, especially in the case of very early decompression or incomplete tSCI.

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来源期刊
CiteScore
4.50
自引率
14.30%
发文量
311
审稿时长
3 months
期刊介绍: The European Journal of Trauma and Emergency Surgery aims to open an interdisciplinary forum that allows for the scientific exchange between basic and clinical science related to pathophysiology, diagnostics and treatment of traumatized patients. The journal covers all aspects of clinical management, operative treatment and related research of traumatic injuries. Clinical and experimental papers on issues relevant for the improvement of trauma care are published. Reviews, original articles, short communications and letters allow the appropriate presentation of major and minor topics.
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