联合二氧化碳激光汽化和博莱霉素注射治疗巨大成人喉血管畸形：二氧化碳激光在耳鼻喉科的创新应用。

IF 2.2 3区医学 Q2 DERMATOLOGY

Lasers in Surgery and Medicine Pub Date : 2024-07-11 DOI:10.1002/lsm.23824

Xiufa Wu, Jing Zhang, Rui Fang, Chunsheng Wei

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引用次数: 0

摘要

研究目的本研究旨在评估二氧化碳激光气化术与博莱霉素注射相结合治疗巨大成人喉血管畸形（HALVAs）的价值：本研究回顾性审查了 13 名成年患者的病历，他们接受了 18 种不同的手术。2009年9月至2023年1月期间，治疗HALVA的方法包括传统的博莱霉素注射和二氧化碳激光汽化联合博莱霉素注射。治疗结果根据管腔收缩程度进行评估：共有 5 名男性和 8 名女性参与了研究，平均年龄为 46.3 岁（22-66 岁）。我们研究中的巨大成人喉血管畸形大于1633.71立方毫米，基底长径大于15毫米。与仅注射博莱霉素组相比，二氧化碳激光汽化和博莱霉素注射联合治疗的效果更好：博莱霉素注射和二氧化碳激光汽化都是安全的治疗方法。结论：博来霉素注射法和二氧化碳激光汽化法都是安全的治疗方法，两者结合治疗巨大成人喉血管畸形可能会取得更好的效果。

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Combined CO2 Laser Vaporization and Bleomycin Injection to Treat Huge Adult Laryngeal Vascular Anomalies: Innovative Application of CO2 Laser in Otolaryngology

Objectives

The aim of this study was to assess the value of CO₂ laser vaporization in treating huge adult laryngeal vascular anomalies (HALVAs) by combining it with bleomycin injection.

Materials and Methods

This study retrospectively reviewed the records of 13 adult patients who underwent 18 different procedures. Methods to treat HALVAs include traditional bleomycin injection and CO₂ laser vaporization combined with bleomycin injection between September 2009 and January 2023. Treatment results were evaluated by the grade of lumen constriction.

Results

A total of five males and eight females, with an average age of 46.3 years (range, 22–66 years), were included in the study. The huge adult laryngeal vascular anomalies in our study were greater than 1633.71 mm³, and the long diameters of the bases were longer than 15 mm. Compared with the bleomycin injection-only group, the results with the CO₂ laser vaporization and bleomycin injection combined were better.

Conclusions

Both bleomycin injection and CO₂ laser vaporization are safe treatment methods. Their combination may produce better results for huge adult laryngeal vascular anomalies.

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来源期刊

Lasers in Surgery and Medicine 医学-外科

CiteScore

5.40

自引率

12.50%

发文量

119

审稿时长

1 months

期刊介绍： Lasers in Surgery and Medicine publishes the highest quality research and clinical manuscripts in areas relating to the use of lasers in medicine and biology. The journal publishes basic and clinical studies on the therapeutic and diagnostic use of lasers in all the surgical and medical specialties. Contributions regarding clinical trials, new therapeutic techniques or instrumentation, laser biophysics and bioengineering, photobiology and photochemistry, outcomes research, cost-effectiveness, and other aspects of biomedicine are welcome. Using a process of rigorous yet rapid review of submitted manuscripts, findings of high scientific and medical interest are published with a minimum delay.