基于门诊患者的阿片类药物治疗参与度和就诊率:无家可归成年人的前瞻性队列研究》。

IF 4.3 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES
Journal of General Internal Medicine Pub Date : 2024-11-01 Epub Date: 2024-07-10 DOI:10.1007/s11606-024-08916-2
Danielle R Fine, Katherine Hart, Natalia Critchley, Yuchiao Chang, Susan Regan, Andrea Joyce, Emily Tixier, Nora Sporn, Jessie Gaeta, Joe Wright, Gina Kruse, Travis P Baggett
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引用次数: 0

摘要

背景:阿片类药物过量疫情对无家可归者的影响尤为严重。美国各地已在无家可归者的医疗机构中设立了基于门诊的阿片类药物治疗(OBOT)项目,但人们对这些项目在吸引和留住这一高度边缘化的患者群体参与成瘾治疗方面取得的成功知之甚少:目的:评估无家可归者参与量身定制的 OBOT 项目的初始参与度和后续参与度的预测因素:设计:前瞻性队列研究,随访 4 个月:共有 148 名无家可归的成年人(≥18 岁)在 1 年内(1/6/2022-1/5/2023)新加入了波士顿无家可归者医疗保健计划(BHPHC)OBOT 项目:主要结果:(1)最初参与 OBOT 计划的情况,即在加入 OBOT 计划后 1 个月内进行了≥2 次额外的 OBOT 就诊;(2)随后参与 OBOT 计划的情况,即在随访的第 2 到第 4 个月期间每月进行一次测量:平均年龄为 41.7 岁(SD 10.2);23.6% 为女性,35.8% 为西班牙裔,12.8% 为非西班牙裔黑人,43.9% 为非西班牙裔白人。超过一半(57.4%)的人最初参与了该计划。在第 2、3 和 4 个月,参加 OBOT 计划的人数分别为 60.8%、50.0% 和 41.2%。四分之一(24.3%)的受试者最初参与了 OBOT 计划,并在随访期间每月参加该计划。参加 OBOT 计划时正在接受住房或住院治疗的参与者(与未接受住房治疗者相比;调整后的几率比 (aORs) = 2.52;95% CI = 1.17-5.44)以及已经服用或开始服用阿片类药物使用障碍 (OUD) 药物的参与者(aOR = 6.53;95% CI = 1.62-26.25)参与的几率更高。年龄越大(aOR = 1.74 per 10-year increment; 95% CI = 1.28-2.38)和初次参与(aOR = 3.50; 95% CI = 1.86-6.59),参与的几率越高:在这项研究中,超过半数的人最初参与了 OBOT 计划,而最初的参与是后续参与 OBOT 计划的有力预测因素。旨在提高 OBOT 项目初始参与度的干预措施,包括以住房和丁丙诺啡起始治疗为重点的干预措施,可能会改善这一边缘化人群的长期治疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Outpatient-Based Opioid Treatment Engagement and Attendance: A Prospective Cohort Study of Homeless-Experienced Adults.

Outpatient-Based Opioid Treatment Engagement and Attendance: A Prospective Cohort Study of Homeless-Experienced Adults.

Background: The opioid overdose epidemic disproportionately impacts people experiencing homelessness. Outpatient-based opioid treatment (OBOT) programs have been established in homeless health care settings across the USA, but little is known about the success of these programs in engaging and retaining this highly marginalized patient population in addiction care.

Objective: To evaluate predictors of initial engagement and subsequent attendance in a homeless-tailored OBOT program.

Design: Prospective cohort study with 4 months of follow-up.

Participants: A total of 148 homeless-experienced adults (≥18 years) who newly enrolled in the Boston Healthcare for the Homeless Program (BHCHP) OBOT program over a 1-year period (1/6/2022-1/5/2023).

Main measures: The primary outcomes were (1) initial OBOT program engagement, defined as having ≥2 additional OBOT visits within 1 month of OBOT enrollment, and (2) subsequent OBOT program attendance, measured monthly from months 2 to 4 of follow-up.

Key results: The average age was 41.7 years (SD 10.2); 23.6% were female, 35.8% were Hispanic, 12.8% were non-Hispanic Black, and 43.9% were non-Hispanic White. Over one-half (57.4%) were initially engaged. OBOT program attendances during months 2, 3, and 4 were 60.8%, 50.0%, and 41.2%, respectively. One-quarter (24.3%) were initially engaged and then attended the OBOT program every month during the follow-up period. Participants in housing or residential treatment programs (vs. unhoused; adjusted odds ratios (aORs) = 2.52; 95% CI = 1.17-5.44) and those who were already on or initiated a medication for opioid use disorder (OUD) (aOR = 6.53; 95% CI = 1.62-26.25) at the time of OBOT enrollment had higher odds of engagement. Older age (aOR = 1.74 per 10-year increment; 95% CI = 1.28-2.38) and initial engagement (aOR = 3.50; 95% CI = 1.86-6.59) conferred higher odds of attendance.

Conclusions: In this study, over half initially engaged with the OBOT program, with initial engagement emerging as a strong predictor of subsequent OBOT program attendance. Interventions aimed at enhancing initial OBOT program engagement, including those focused on housing and buprenorphine initiation, may improve longer-term outcomes in this marginalized population.

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来源期刊
Journal of General Internal Medicine
Journal of General Internal Medicine 医学-医学:内科
CiteScore
7.70
自引率
5.30%
发文量
749
审稿时长
3-6 weeks
期刊介绍: The Journal of General Internal Medicine is the official journal of the Society of General Internal Medicine. It promotes improved patient care, research, and education in primary care, general internal medicine, and hospital medicine. Its articles focus on topics such as clinical medicine, epidemiology, prevention, health care delivery, curriculum development, and numerous other non-traditional themes, in addition to classic clinical research on problems in internal medicine.
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