揭示衰老、昼夜节律与癌症之间的联系:循证分析的启示。

IF 7 2区 医学 Q1 ONCOLOGY
Dechao Feng, Yuhan Xiao, Jie Wang, Ruicheng Wu, Zhouting Tuo, Koo Han Yoo, Wuran Wei, Dilinaer Wusiman, Zhipeng Wang, Dengxiong Li, Yubo Yang, William C Cho, Mang Ke
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引用次数: 0

摘要

衰老与昼夜节律之间的联系已有几十年的历史,但它们之间的分子相互作用却一直不为人知,尤其是在癌症方面。在这种情况下,我们通过文献计量分析总结了该领域目前的研究现状和问题。我们检索了 PubMed 和 Web of Science 数据库中的文献。总体而言,癌症领域有关衰老和昼夜节律的论文数量呈上升趋势。来自美国、德国、意大利、中国和英国的研究人员的研究成果较多。发表论文最多的三个机构分别是加利福尼亚大学系统、法国研究型大学联盟(UDICE-French Research Universities)和德克萨斯大学系统。目前的研究热点包括氧化应激、乳腺癌、褪黑激素、细胞周期、卡路里限制、前列腺癌和 NF-KB。总之,文献计量分析的结果表明,许多方法都涉及癌症中衰老与昼夜节律之间复杂的相互作用。这些既有的和新兴的研究方向为我们探索癌症中衰老和昼夜节律的调控机制提供了指导,也为开发新的研究途径提供了参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Unraveling links between aging, circadian rhythm and cancer: Insights from evidence-based analysis.

Aging and circadian rhythms have been connected for decades, but their molecular interaction has remained unknown, especially for cancers. In this situation, we summarized the current research actuality and problems in this field using the bibliometric analysis. Publications in the PubMed and Web of Science databases were retrieved. Overall, there is a rising trend in the publication volume regarding aging and circadian rhythms in the field of cancer. Researchers from USA, Germany, Italy, China and England have greater studies than others. Top three publication institutions are University of California System, UDICE-French Research Universities and University of Texas System. Current research hotspots include oxidative stress, breast cancer, melatonin, cell cycle, calorie restriction, prostate cancer and NF-KB. In conclusion, results generated by bibliometric analysis indicate that many approaches involve in the complex interactions between aging and circadian rhythm in cancer. These established and emerging research directions guide our exploration of the regulatory mechanisms of aging and circadian rhythms in cancer and provide a reference for developing new research avenues.

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来源期刊
自引率
9.80%
发文量
1726
审稿时长
4.5 months
期刊介绍: Chinese Journal of Cancer Research (CJCR; Print ISSN: 1000-9604; Online ISSN:1993-0631) is published by AME Publishing Company in association with Chinese Anti-Cancer Association.It was launched in March 1995 as a quarterly publication and is now published bi-monthly since February 2013. CJCR is published bi-monthly in English, and is an international journal devoted to the life sciences and medical sciences. It publishes peer-reviewed original articles of basic investigations and clinical observations, reviews and brief communications providing a forum for the recent experimental and clinical advances in cancer research. This journal is indexed in Science Citation Index Expanded (SCIE), PubMed/PubMed Central (PMC), Scopus, SciSearch, Chemistry Abstracts (CA), the Excerpta Medica/EMBASE, Chinainfo, CNKI, CSCI, etc.
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