聚苯乙烯磺酸钙诱发的结肠炎：利用红外光谱对晶体性质进行高级表征

IF 3.9 2区医学 Q1 UROLOGY & NEPHROLOGY

Clinical Kidney Journal Pub Date : 2024-07-05 DOI:10.1093/ckj/sfae210

Helena Vidal, Vilma Salgado, Patrícia Alves, Nuno Moreira Fonseca1, Vincent Frochot, Aníbal Ferreira

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引用次数: 0

摘要

传统的钾结合剂用于治疗高钾血症，但普遍存在胃肠道副作用，结肠结晶损伤虽然罕见，但却可能致命。在本报告中，我们描述了一例 82 岁男性高钾血症和聚苯乙烯磺酸钙晶体相关结肠坏死病例。传统的诊断方法是通过显微镜检查晶体形态和偏振。我们的研究通过使用红外光谱分析晶体的物理特性，增强了晶体鉴定能力。据我们所知，这是首次描述聚苯乙烯磺酸钙的红外光谱。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Calcium Polystyrene Sulfonate Induced Colitis: Advanced characterization of crystal nature with infrared spectroscopy

Classical potassium binders are used in the treatment of hyperkalemia and are widely associated with gastrointestinal side effects, with crystal colonic injury being rare but potentially fatal. In this report, we describe the case of an 82-year-old male with hyperkalemia and calcium polystyrene sulfonate crystal associated colonic necrosis. Traditionally, this diagnosis has relied on the examination of crystal morphology and polarization through microscopy. Our study enhances crystal identification by incorporating an analysis of the physical characteristics of the crystals using infrared spectroscopy. This is the first description, to our knowledge, of calcium polystyrene sulfonate infrared spectrum.

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来源期刊

Clinical Kidney Journal Medicine-Transplantation

CiteScore

6.70

自引率

10.90%

发文量

242

审稿时长

8 weeks

期刊介绍： About the Journal Clinical Kidney Journal: Clinical and Translational Nephrology (ckj), an official journal of the ERA-EDTA (European Renal Association-European Dialysis and Transplant Association), is a fully open access, online only journal publishing bimonthly. The journal is an essential educational and training resource integrating clinical, translational and educational research into clinical practice. ckj aims to contribute to a translational research culture among nephrologists and kidney pathologists that helps close the gap between basic researchers and practicing clinicians and promote sorely needed innovation in the Nephrology field. All research articles in this journal have undergone peer review.