Nayani P Madarasingha, Harshini Thabrew, Silk Uhrlass, Surammika Eriyagama, Dieter Reinal, Primali I Jayasekera, Pietro Nenoff
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引用次数: 0
摘要
在过去几年中，包括斯里兰卡在内的印度次大陆出现了一种顽固的皮癣，给该地区带来了严重的公共卫生问题。一种新出现的物种--吲哚癣毛癣菌（Trichophyton indotineae），最初被描述为萌芽癣毛癣菌（Trichophyton mentagrophytes ITS genotype VIII），被认为是造成这种快速传播、主要对特比萘芬耐药的皮癣病的罪魁祸首。顽固性皮癣对皮肤科医生来说是一项挑战，在治疗的早期阶段了解致病菌的种类和抗真菌药物的敏感性将非常有价值。我们报告了斯里兰卡由 T. indotineae 引起的皮癣患者的一系列病例。这是斯里兰卡首次发现这种对特比萘芬高度耐药的菌株，皮肤科医生和医疗政策制定者应认真对待这种菌株的存在，以便更好地管理该国的皮癣感染和抗真菌药物管理。
Dermatophytosis Caused by Trichophyton indotineae (Trichophyton mentagrophytes ITS Genotype VIII) in Sri Lanka.
Over the past few years, a recalcitrant dermatophytosis has been observed on the Indian subcontinent, including Sri Lanka, which has caused a major public health issue in the region. An emerging species, Trichophyton indotineae, first described as Trichophyton mentagrophytes ITS genotype VIII, is thought to be responsible for this fast-spreading, mostly terbinafine-resistant dermatophytosis. Recalcitrant dermatophytosis is a challenge to dermatologists, and knowing the causative species and antifungal sensitivity in the earlier stage of management would be invaluable. We report a case series of patients with dermatophytosis caused by T. indotineae in Sri Lanka. This is the first detection of this highly terbinafine-resistant strain in Sri Lanka, and existence of this species should be taken seriously by dermatologists and healthcare policymakers for better management of tinea infections and antifungal stewardship in the country.
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The American Journal of Tropical Medicine and Hygiene, established in 1921, is published monthly by the American Society of Tropical Medicine and Hygiene. It is among the top-ranked tropical medicine journals in the world publishing original scientific articles and the latest science covering new research with an emphasis on population, clinical and laboratory science and the application of technology in the fields of tropical medicine, parasitology, immunology, infectious diseases, epidemiology, basic and molecular biology, virology and international medicine.
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