香港市民从膳食摄入多芳香族碳氢化合物的情况。

IF 2.3 3区 农林科学 Q2 CHEMISTRY, APPLIED
Stephen W C Chung, Melissa P S Liu, Kenny K C Wong, Gabriel Y S Chan
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引用次数: 0

摘要

多芳烃(PAHs)在环境和食物中无处不在。粮农组织/世卫组织食品添加剂联合专家委员会认为,有 13 种多环芳烃在体外和体内具有致癌性和遗传毒性。食物是成年非吸烟者摄入多环芳烃的主要来源,占总摄入量的 90% 以上。这项研究在香港收集了 300 个食物样本,分析 16 种欧盟优先考虑的 PAHs 含量,以及本港成年人从这些食物摄入 PAHs 的情况和相关的健康风险。检测到的最主要多环芳烃是菊烯(14.4%),其次是苯并[c]芴(11.2%)、苯并[a]蒽(10.6%)和苯并[b]荧蒽(7.8%)。一般消费者从膳食摄入苯并[a]芘(BaP)和多环芳烃 4(BaP、CHR、BaA 和 BbFA 的总和)的下限和上限分别为 0.13-0.90 纳克/千克体重/天和 1.4-4.2 纳克/千克体重/天。在下限法中,谷物及其制品对普通消费者摄入苯并[a]芘和多环芳烃[PAH4]的影响超过 50%。采用暴露限值法评估消费者的健康风险。计算得出的摄入量一般和摄入量高的消费者(第 90 百分位数)的苯并[a]芘和多环芳烃[PAH4]暴露限值均大于 50,000 ,表明对香港市民健康的影响不大。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dietary exposure to polyaromatic hydrocarbons of the Hong Kong population.

Polyaromatic hydrocarbons (PAHs) are ubiquitous in the environment and food. The Joint FAO/WHO Expert Committee on Food Additives concluded 13 individual PAHs are carcinogenic and genotoxic in vitro and in vivo. Food is recognized as the main source of exposure to PAHs for adult non-smokers, which contributed to more than 90% of total exposure. In this study, 300 food samples were collected in Hong Kong, analysed the levels of 16 European Union priority PAHs, the dietary exposure to these PAHs by the local adult population from these food items, and the associated health risk. The most predominant detectable PAH was chrysene (CHR) (14.4%), followed by benzo[c]fluorene (11.2%), benzo[a]anthracene (BaA) (10.6%) and benzo[b]fluoranthene (BbFA) (7.8%). The dietary exposures for average consumers of benzo[a]pyrene (BaP) and PAH4 (sum of BaP, CHR, BaA and BbFA) were 0.13-0.90 and 1.4-4.2 ng/kg bw/day respectively for lower and upper bound approaches. Cereal and its products contributed more than 50% to BaP and PAH4 for average consumers in a lower-bound approach. The margin of exposure (MOE) approach was used to assess the health risks of consumers. The calculated MOE values for both BaP and PAH4 of the average and high consumers (90th percentile) were >50,000, indicating a low concern for the health of the Hong Kong population.

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来源期刊
CiteScore
7.40
自引率
6.90%
发文量
136
审稿时长
3 months
期刊介绍: Food Additives & Contaminants: Part A publishes original research papers and critical reviews covering analytical methodology, occurrence, persistence, safety evaluation, detoxification and regulatory control of natural and man-made additives and contaminants in the food and animal feed chain. Papers are published in the areas of food additives including flavourings, pesticide and veterinary drug residues, environmental contaminants, plant toxins, mycotoxins, marine biotoxins, trace elements, migration from food packaging, food process contaminants, adulteration, authenticity and allergenicity of foods. Papers are published on animal feed where residues and contaminants can give rise to food safety concerns. Contributions cover chemistry, biochemistry and bioavailability of these substances, factors affecting levels during production, processing, packaging and storage; the development of novel foods and processes; exposure and risk assessment.
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