兔子身上的横纹肌肉瘤

IF 1.3 3区农林科学 Q2 VETERINARY SCIENCES

Topics in companion animal medicine Pub Date : 2024-07-01 DOI:10.1016/j.tcam.2024.100892

Logan Kopp , Michael Garner , Kara Priest

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引用次数: 0

摘要

一只老年荷兰罗普兔因急性跛行前来就诊。经诊断，该兔右侧股骨远端发生病理性骨折，并伴有多形性横纹肌肉瘤，初次就诊时的分期X光片显示没有明显转移。肢体被截肢并送去做显微镜检查。免疫组化评估显示，肿瘤细胞的desmin和MyoD1阳性，细胞角蛋白AE1/AE3、CD204、IBA-1和SMA阴性。经大体、组织学和免疫组化评估，确诊为多形性横纹肌肉瘤。患者在截肢 396 天后死亡，尸检显示肉瘤转移至多个器官。

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Rhabdomyosarcoma in a Rabbit

A geriatric Holland Lop rabbit presented for acute lameness. A pathologic fracture of the right distal femur associated with a pleomorphic rhabdomyosarcoma was diagnosed, and staging radiographs showed no overt metastasis upon initial presentation. The limb was amputated and submitted for microscopic examination. Immunohistochemical evaluation revealed the neoplastic cells were positive for desmin and MyoD1, and negative for cytokeratin AE1/AE3, CD204, IBA-1, and SMA. Gross, histologic, and immunohistochemical evaluation confirmed a diagnosis of pleomorphic rhabdomyosarcoma. The patient died 396 days after amputation, and a post-mortem examination showed metastatic sarcoma to multiple organs.

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来源期刊

Topics in companion animal medicine 农林科学-兽医学

CiteScore

2.30

自引率

0.00%

发文量

审稿时长

88 days

期刊介绍： Published quarterly, Topics in Companion Animal Medicine is a peer-reviewed veterinary scientific journal dedicated to providing practitioners with the most recent advances in companion animal medicine. The journal publishes high quality original clinical research focusing on important topics in companion animal medicine.