{"title":"用于控制眼球拉长的软性周边接触镜(SPACE):双盲随机对照试验的 1 年结果。","authors":"","doi":"10.1016/j.clae.2024.102256","DOIUrl":null,"url":null,"abstract":"<div><h3>Purpose</h3><p>To examine the safety and efficacy of soft multifocal contact lenses on slowing the rate of myopia progression.</p></div><div><h3>Methods</h3><p>A prospective, randomized, double-masked clinical trial was conducted including 115 children (55 boys and 60 girls) aged 8 to 15 years. Children were assigned to wear one of two daily disposable soft contact lens designs; a multifocal design (Pegavision) or a dual-focus design (MiSight, Coopervision) in both eyes for at least 8 h per day for one year. All contact lenses were replaced on a daily basis. Measurements were obtained using a logMAR vision meter, including objective refraction, handheld retinoscopy, high (96 %) and low (12 %) contrast sensitivity, and distance and near visual acuity. Axial length was measured every 6 months.</p></div><div><h3>Results</h3><p>After one year, the spherical equivalent refractive error and axial length of the experimental group (Pegavision) increased by −0.50 ± 0.48 D and 0.24 ± 0.16 mm, respectively, in the right eye and −0.47 ± 0.37 D and 0.23 ± 0.16 mm, respectively, in the left eye. The spherical equivalent refractive error and axial length of the control group (MiSight) increased by −0.48 ± 0.47 D and 0.22 ± 0.13 mm, respectively, in the right eye and by −0.50 ± 0.44 D and 0.23 ± 0.14 mm, respectively, in the left eye, with no significant differences observed between the two lens types.</p></div><div><h3>Conclusions</h3><p>The one-year results from this clinical trial show that the multifocal soft contact lenses used in the experimental group have a similar myopia control efficacy with respect to spherical equivalent refraction and axial length elongation as a commercially available dual focus soft contact lens design.</p></div>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":null,"pages":null},"PeriodicalIF":4.1000,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1367048424001486/pdfft?md5=2aa6edb4a38b9f82720d5c4e0fe47f70&pid=1-s2.0-S1367048424001486-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Soft peripheral contact lens for eye elongation control (SPACE): 1-year results of a double-blinded randomized controlled trial\",\"authors\":\"\",\"doi\":\"10.1016/j.clae.2024.102256\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Purpose</h3><p>To examine the safety and efficacy of soft multifocal contact lenses on slowing the rate of myopia progression.</p></div><div><h3>Methods</h3><p>A prospective, randomized, double-masked clinical trial was conducted including 115 children (55 boys and 60 girls) aged 8 to 15 years. Children were assigned to wear one of two daily disposable soft contact lens designs; a multifocal design (Pegavision) or a dual-focus design (MiSight, Coopervision) in both eyes for at least 8 h per day for one year. All contact lenses were replaced on a daily basis. Measurements were obtained using a logMAR vision meter, including objective refraction, handheld retinoscopy, high (96 %) and low (12 %) contrast sensitivity, and distance and near visual acuity. Axial length was measured every 6 months.</p></div><div><h3>Results</h3><p>After one year, the spherical equivalent refractive error and axial length of the experimental group (Pegavision) increased by −0.50 ± 0.48 D and 0.24 ± 0.16 mm, respectively, in the right eye and −0.47 ± 0.37 D and 0.23 ± 0.16 mm, respectively, in the left eye. The spherical equivalent refractive error and axial length of the control group (MiSight) increased by −0.48 ± 0.47 D and 0.22 ± 0.13 mm, respectively, in the right eye and by −0.50 ± 0.44 D and 0.23 ± 0.14 mm, respectively, in the left eye, with no significant differences observed between the two lens types.</p></div><div><h3>Conclusions</h3><p>The one-year results from this clinical trial show that the multifocal soft contact lenses used in the experimental group have a similar myopia control efficacy with respect to spherical equivalent refraction and axial length elongation as a commercially available dual focus soft contact lens design.</p></div>\",\"PeriodicalId\":49087,\"journal\":{\"name\":\"Contact Lens & Anterior Eye\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.1000,\"publicationDate\":\"2024-07-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S1367048424001486/pdfft?md5=2aa6edb4a38b9f82720d5c4e0fe47f70&pid=1-s2.0-S1367048424001486-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Contact Lens & Anterior Eye\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1367048424001486\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Contact Lens & Anterior Eye","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1367048424001486","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
Soft peripheral contact lens for eye elongation control (SPACE): 1-year results of a double-blinded randomized controlled trial
Purpose
To examine the safety and efficacy of soft multifocal contact lenses on slowing the rate of myopia progression.
Methods
A prospective, randomized, double-masked clinical trial was conducted including 115 children (55 boys and 60 girls) aged 8 to 15 years. Children were assigned to wear one of two daily disposable soft contact lens designs; a multifocal design (Pegavision) or a dual-focus design (MiSight, Coopervision) in both eyes for at least 8 h per day for one year. All contact lenses were replaced on a daily basis. Measurements were obtained using a logMAR vision meter, including objective refraction, handheld retinoscopy, high (96 %) and low (12 %) contrast sensitivity, and distance and near visual acuity. Axial length was measured every 6 months.
Results
After one year, the spherical equivalent refractive error and axial length of the experimental group (Pegavision) increased by −0.50 ± 0.48 D and 0.24 ± 0.16 mm, respectively, in the right eye and −0.47 ± 0.37 D and 0.23 ± 0.16 mm, respectively, in the left eye. The spherical equivalent refractive error and axial length of the control group (MiSight) increased by −0.48 ± 0.47 D and 0.22 ± 0.13 mm, respectively, in the right eye and by −0.50 ± 0.44 D and 0.23 ± 0.14 mm, respectively, in the left eye, with no significant differences observed between the two lens types.
Conclusions
The one-year results from this clinical trial show that the multifocal soft contact lenses used in the experimental group have a similar myopia control efficacy with respect to spherical equivalent refraction and axial length elongation as a commercially available dual focus soft contact lens design.
期刊介绍:
Contact Lens & Anterior Eye is a research-based journal covering all aspects of contact lens theory and practice, including original articles on invention and innovations, as well as the regular features of: Case Reports; Literary Reviews; Editorials; Instrumentation and Techniques and Dates of Professional Meetings.