与 COVID-19 相关的粘液瘤病导航:内窥镜分级、放射学相关性和治疗效果

Yamini Gupta, Jagram Verma, Krishna Valecha
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引用次数: 0

摘要

全球 COVID-19 大流行带来了多方面的医疗挑战,包括 COVID-19 相关粘液瘤病(CAM)的出现。本研究调查了印度中部地区 CAM 的人口统计学、临床表现、内窥镜分级、放射学相关性、治疗方式和结果。该研究对 312 名 CAM 患者(2021 年 4 月至 6 月)进行了回顾性分析。数据包括人口统计学、临床概况、内窥镜和放射学检查结果、实验室结果和治疗方法。采用新颖的内窥镜分级系统来评估粘孢子菌病病变的严重程度。统计分析包括卡方检验。在312名患者中,65%为男性,82%有合并症,84%伴有面部肿胀。内镜分级与放射学表现(P < 0.05)和术中发现相关。手术清创和抗真菌治疗是常见的治疗方法,但临床效果各不相同。晚期患者的死亡率为 13%。这项研究强调了内窥镜分级在风险分层和预后判断中的作用。研究结果有助于丰富CAM管理知识,强调了有针对性干预措施的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Navigating COVID-19-associated mucormycosis: endoscopic grading, radiological correlations, and treatment outcomes
The global COVID-19 pandemic has brought forth multifaceted healthcare challenges, including the emergence of COVID-19-associated mucormycosis (CAM). This study investigates demographics, clinical presentation, endoscopic grading, radiological correlations, treatment modalities, and outcomes of CAM in Central India. A retrospective analysis of 312 CAM patients (April-June 2021). Data included demographics, clinical profiles, endoscopic and radiological findings, laboratory results, and treatments. A novel endoscopic grading system was utilized to assess the severity of mucormycosis lesions. Statistical analysis, including chi-squared tests, was performed. Among 312 patients, 65% were male, 82% had comorbidities, and 84% presented with facial swelling. Endoscopic grading correlated with radiological manifestations (p < 0.05) and intraoperative findings. Surgical debridement and antifungal therapy were common treatments, yielding varied clinical outcomes. Mortality was 13% in advanced grades. This study underscores the role of endoscopic grading in risk stratification and prognosis. Findings contribute to CAM management knowledge, underscoring tailored interventions’ significance.
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