一只 1 岁猫皮肤黑色素细胞瘤的临床病理描述

IF 1.2 4区农林科学 Q3 VETERINARY SCIENCES

Veterinary clinical pathology Pub Date : 2024-06-21 DOI:10.1111/vcp.13361

Min-Kyung Bae, Ji-Woo Cha, Ha-Young Lim, Chae-Wook Kim, Se-Hee Han, Jung-Hyang Sur, Ji-Young Yhee

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引用次数: 0

摘要

本文报告了一只 1 岁猫患的猫皮肤黑色素细胞瘤。报告中包括了这只小猫皮肤黑色素细胞瘤的细胞学、组织学和免疫组化特征。经组织学诊断，猫头部的单发黑色结节为上皮样黑色素细胞瘤。免疫组化结果显示，肿瘤黑色素细胞对 S100 和 MelanA 抗体有免疫反应，但对 PNL2 抗体没有免疫反应。尽管有丝分裂计数（17/10HPFs）和 Ki67 指数（33%）较高，提示为恶性黑色素瘤，但该患者在 5 个月后的预后良好。瘤细胞的有丝分裂活性可能无法为猫黑色素细胞瘤提供可靠的预测。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Clinicopathologic description of a cutaneous melanocytic tumor in a 1-year-old cat

A feline cutaneous melanocytic tumor in a 1-year-old cat is reported. The cytologic, histologic, and immunohistochemical characteristics of the pediatric feline cutaneous melanocytoma are included. A solitary, black-colored nodule on the head was histologically diagnosed as the epithelioid type of melanocytoma. Immunohistochemically, the neoplastic melanocytes demonstrated immunoreactivity to the S100 and MelanA antibodies but not to the PNL2 antibody. Despite high mitotic counts (17/10HPFs) and a Ki67 index (33%) suggesting malignant melanoma, the patient exhibited a favorable 5-month outcome. The mitotic activity of the neoplastic cells may not provide a reliable prediction for feline melanocytic tumors.

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来源期刊

Veterinary clinical pathology 农林科学-兽医学

CiteScore

1.70

自引率

16.70%

发文量

133

审稿时长

18-36 weeks

期刊介绍： Veterinary Clinical Pathology is the official journal of the American Society for Veterinary Clinical Pathology (ASVCP) and the European Society of Veterinary Clinical Pathology (ESVCP). The journal''s mission is to provide an international forum for communication and discussion of scientific investigations and new developments that advance the art and science of laboratory diagnosis in animals. Veterinary Clinical Pathology welcomes original experimental research and clinical contributions involving domestic, laboratory, avian, and wildlife species in the areas of hematology, hemostasis, immunopathology, clinical chemistry, cytopathology, surgical pathology, toxicology, endocrinology, laboratory and analytical techniques, instrumentation, quality assurance, and clinical pathology education.