在微物理系统中模拟先天性免疫系统。

IF 6.1 2区工程技术 Q1 BIOCHEMICAL RESEARCH METHODS

Lab on a Chip Pub Date : 2024-07-03 DOI:10.1039/D3LC00812F

Michael J. Rupar, Hannah Hanson, Stephanie Rogers, Brianna Botlick, Steven Trimmer and James J. Hickman

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引用次数: 0

摘要

这篇评论旨在强调免疫反应建模如何随着时间的推移而适应利用微生理系统。这里涉及的主题将讨论人体各系统中免疫系统不可或缺的组成部分，以及如何利用这些系统对这些相互作用进行建模。通过使用微观生理学系统，我们不仅扩展了免疫细胞基本信息的基础，还深入了解了免疫细胞如何在整个人体系统中独立和协同工作。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Modelling the innate immune system in microphysiological systems

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Modelling the innate immune system in microphysiological systems

This critical review aims to highlight how modeling of the immune response has adapted over time to utilize microphysiological systems. Topics covered here will discuss the integral components of the immune system in various human body systems, and how these interactions are modeled using these systems. Through the use of microphysiological systems, we have not only expanded on foundations of basic immune cell information, but have also gleaned insight on how immune cells work both independently and collaboratively within an entire human body system.

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来源期刊

Lab on a Chip 工程技术-化学综合

CiteScore

11.10

自引率

8.20%

发文量

434

审稿时长

2.6 months

期刊介绍： Lab on a Chip is the premiere journal that publishes cutting-edge research in the field of miniaturization. By their very nature, microfluidic/nanofluidic/miniaturized systems are at the intersection of disciplines, spanning fundamental research to high-end application, which is reflected by the broad readership of the journal. Lab on a Chip publishes two types of papers on original research: full-length research papers and communications. Papers should demonstrate innovations, which can come from technical advancements or applications addressing pressing needs in globally important areas. The journal also publishes Comments, Reviews, and Perspectives.