从哪里来线粒体 mRNA 离去，蛋白质归来

IF 27.7 1区生物学 Q1 CELL BIOLOGY

Cell metabolism Pub Date : 2024-07-02 DOI:10.1016/j.cmet.2024.06.002

Kevin A. Janssen, Angela Song

引用次数: 0

摘要

以前曾有报道称，小肽在线粒体 rRNA 中编码，并由细胞质核糖体翻译。在本期《细胞新陈代谢》（Cell Metabolism）杂志上，Hu 等人利用质谱法鉴定了一种由线粒体 mRNA 编码的细胞膜翻译蛋白质，这种蛋白质竟然被靶向回到线粒体基质中。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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From whence it came: Mitochondrial mRNA leaves, a protein returns

Small peptides have previously been reported to be encoded in mitochondrial rRNA and translated by cytosolic ribosomes. In this issue of Cell Metabolism, Hu et al. use mass spectrometry to identify a cytosolically translated protein, encoded instead in mitochondrial mRNA, that is surprisingly targeted back into the mitochondrial matrix.

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来源期刊

Cell metabolism 生物-内分泌学与代谢

CiteScore

48.60

自引率

1.40%

发文量

173

审稿时长

2.5 months

期刊介绍： Cell Metabolism is a top research journal established in 2005 that focuses on publishing original and impactful papers in the field of metabolic research.It covers a wide range of topics including diabetes, obesity, cardiovascular biology, aging and stress responses, circadian biology, and many others. Cell Metabolism aims to contribute to the advancement of metabolic research by providing a platform for the publication and dissemination of high-quality research and thought-provoking articles.