异体造血干细胞移植后过敏性肺炎缓解

IF 2.4 Q2 RESPIRATORY SYSTEM
Yumi Inukai Motokura , Hisao Higo , Chiaki Matsumoto , Mari Uno , Kanako Fujiwara , Toshiki Terao , Satoko Makimoto , Fumiyo Higaki , Ken-ichi Matsuoka , Fumiaki Tokioka , Yoshinobu Maeda , Nobuaki Miyahara
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引用次数: 0

摘要

一名 50 岁的男子在接受环境吸入挑战测试后,由于症状、实验室检测结果和计算机断层扫描图像恶化,被诊断为由其酒吧环境引起的超敏性肺炎。尽管他接受了泼尼松龙 20 毫克/天的治疗,但超敏性肺炎还是加剧了。患者因骨髓增生异常综合症接受了与人类白细胞抗原匹配的非亲属捐赠者的异基因造血干细胞移植(HSCT)。造血干细胞移植后未发现超敏性肺炎加重。一项环境吸入挑战试验证实,造血干细胞移植后超敏性肺炎得到缓解。本病例表明,造血干细胞移植可缓解超敏性肺炎。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Remission of hypersensitivity pneumonitis after allogeneic hematopoietic stem cell transplantation

A 50-year-old man was diagnosed with hypersensitivity pneumonitis caused by the environment of his bar owing to worsening symptoms, laboratory test results, and computed tomography images after an environmental inhalation challenge test. His hypersensitivity pneumonitis exacerbated despite receiving prednisolone 20 mg/day. The patient underwent allogeneic hematopoietic stem cell transplantation (HSCT) from a human leukocyte antigen-matched unrelated donor for myelodysplastic syndrome. No exacerbation of hypersensitivity pneumonitis was observed after HSCT. An environmental inhalation challenge test involving exposure to his bar confirmed the remission of hypersensitivity pneumonitis after HSCT. This case demonstrates that hypersensitivity pneumonitis can be remitted by HSCT.

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来源期刊
Respiratory investigation
Respiratory investigation RESPIRATORY SYSTEM-
CiteScore
4.90
自引率
6.50%
发文量
114
审稿时长
64 days
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