Emma J P N Gram, Ellen Moseholm, Anne B Nørløv, Charlotte Wilken-Jensen, Kristina Thorsteinsson, Birgitte T Pedersen, Sussie M Jørgensen, Jesper Bonde, Lars H Omland, Anne-Mette Lebech, Nina Weis
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引用次数: 0
摘要
目的评估在常规HIV关怀中对感染HIV的妇女(WLWH)进行综合宫颈癌筛查(CCS)是否会提高筛查的依从性,并描述人乳头状瘤病毒(HPV)特异性基因型的流行情况和细胞异常的发生率:设计:队列研究:纳入 2013-2019 年间接受联合 CCS 和 HIV 护理提议的 WLWH(第 1 组)、拒绝接受提议的 WLWH(第 2 组)以及未在 HIV 护理中提供 CCS 的 WLWH(第 3 组)。数据收集自丹麦艾滋病队列研究(The Danish HIV Cohort Study)和丹麦病理数据库(The Danish Pathology Data Bank)。如果WLWH每年都接受筛查,则定义为符合CCS计划:结果:共纳入了 804 名 WLWH。与拒绝接受CCS的WLWH(第2组;n = 232)的10-16%和未被邀请接受CCS的WLWH(第3组;n = 354)的11-25%相比,在所有研究年份中接受CCS的WLWH(第1组;n = 218)的筛查依从性明显更高,达到22-99%。三组之间在HPV特异性基因型的流行率和细胞异常的发生率方面没有明显差异:结论:将针对WLWH的CCS整合到常规HIV护理中可提高CCS指南的依从性。因此,联合服务是将 WLWH 纳入 HIV 护理并提供预防服务的一个机会。
Cervical cancer screening integrated in routine clinical care of women with HIV.
Objective: To evaluate if integrated cervical cancer screening (CCS) for women with HIV (WWH) in routine HIV care resulted in increased adherence to screening, and to describe the prevalence of human papillomavirus (HPV)-specific genotypes and the incidence of cellular abnormalities.
Design: Cohort study.
Methods: WWH who accepted the offer of combined CCS and HIV care (group 1), WWH who declined the offer (group 2), and WWH not offered CCS within HIV care (group 3) between 2013 and 2019 were included. Data was collected from The Danish HIV Cohort Study and The Danish Pathology Data Bank. Adherence to the CCS program was defined as fulfilled if WWH were screened annually.
Results: A total of 804 WWH were included. WWH who accepted CCS within HIV care (group 1; n = 218) had significantly higher adherence to screening in all study years 22-99% compared with the WWH who declined CCS (group 2; n = 232) 10-16% and WWH who were not invited for CCS (group 3; n = 354) 11-25%. There was no significant difference in the prevalence of HPV-specific genotypes and incidence of cellular abnormalities among the three groups.
Conclusion: Integrating CCS for WWH in routine HIV care resulted in higher adherence to the CCS guidelines. Combined services thereby represent an opportunity to engage WWH in HIV care into preventive services.
期刊介绍:
Publishing the very latest ground breaking research on HIV and AIDS. Read by all the top clinicians and researchers, AIDS has the highest impact of all AIDS-related journals. With 18 issues per year, AIDS guarantees the authoritative presentation of significant advances. The Editors, themselves noted international experts who know the demands of your work, are committed to making AIDS the most distinguished and innovative journal in the field. Submitted articles undergo a preliminary review by the editor. Some articles may be returned to authors without further consideration. Those being considered for publication will undergo further assessment and peer-review by the editors and those invited to do so from a reviewer pool.