Camille Moeckel, Lauren Gaydosh, Lisa Schneper, Colter Mitchell, Daniel A. Notterman
{"title":"物质匮乏与儿童端粒长度","authors":"Camille Moeckel, Lauren Gaydosh, Lisa Schneper, Colter Mitchell, Daniel A. Notterman","doi":"10.1111/cdev.14126","DOIUrl":null,"url":null,"abstract":"Telomere length (TL) serves as a biomarker of exposure to stressors, including material hardship. Data from the Future of Families and Child Wellbeing Study (1998–2015) were utilized to determine whether prior material hardship was associated with shorter salivary TL at years 9 and 15. 49% of the year 9 study population were female, 49% were Black, and 25% were Hispanic. At year 9 (<i>N</i> = 1990), regression analyses found a significant association between prior material hardship and shorter TL (<i>β</i> = −.005, <i>p</i> < .01). Additionally, at year 15 (<i>N</i> = 1874), material hardship experienced during infancy and toddlerhood was associated with shorter TL (<i>β</i> = −.009, <i>p</i> < .01), pointing toward infancy and toddlerhood as a sensitive period.","PeriodicalId":3,"journal":{"name":"ACS Applied Electronic Materials","volume":null,"pages":null},"PeriodicalIF":4.3000,"publicationDate":"2024-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Material hardship and telomere length in children\",\"authors\":\"Camille Moeckel, Lauren Gaydosh, Lisa Schneper, Colter Mitchell, Daniel A. Notterman\",\"doi\":\"10.1111/cdev.14126\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Telomere length (TL) serves as a biomarker of exposure to stressors, including material hardship. Data from the Future of Families and Child Wellbeing Study (1998–2015) were utilized to determine whether prior material hardship was associated with shorter salivary TL at years 9 and 15. 49% of the year 9 study population were female, 49% were Black, and 25% were Hispanic. At year 9 (<i>N</i> = 1990), regression analyses found a significant association between prior material hardship and shorter TL (<i>β</i> = −.005, <i>p</i> < .01). Additionally, at year 15 (<i>N</i> = 1874), material hardship experienced during infancy and toddlerhood was associated with shorter TL (<i>β</i> = −.009, <i>p</i> < .01), pointing toward infancy and toddlerhood as a sensitive period.\",\"PeriodicalId\":3,\"journal\":{\"name\":\"ACS Applied Electronic Materials\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.3000,\"publicationDate\":\"2024-06-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ACS Applied Electronic Materials\",\"FirstCategoryId\":\"102\",\"ListUrlMain\":\"https://doi.org/10.1111/cdev.14126\",\"RegionNum\":3,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ENGINEERING, ELECTRICAL & ELECTRONIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Electronic Materials","FirstCategoryId":"102","ListUrlMain":"https://doi.org/10.1111/cdev.14126","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, ELECTRICAL & ELECTRONIC","Score":null,"Total":0}
Telomere length (TL) serves as a biomarker of exposure to stressors, including material hardship. Data from the Future of Families and Child Wellbeing Study (1998–2015) were utilized to determine whether prior material hardship was associated with shorter salivary TL at years 9 and 15. 49% of the year 9 study population were female, 49% were Black, and 25% were Hispanic. At year 9 (N = 1990), regression analyses found a significant association between prior material hardship and shorter TL (β = −.005, p < .01). Additionally, at year 15 (N = 1874), material hardship experienced during infancy and toddlerhood was associated with shorter TL (β = −.009, p < .01), pointing toward infancy and toddlerhood as a sensitive period.
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