甲状旁腺腺瘤表现为多发性棕色肿瘤和严重的无症状高钙血症。

IF 0.7 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM
Acta Endocrinologica-Bucharest Pub Date : 2023-10-01 Epub Date: 2024-06-24 DOI:10.4183/aeb.2023.508
D V Wasnik, R S Khot, P P Joshi, B D Rathod, U Narang, C Ratnaparkhi
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引用次数: 0

摘要

简介原发性甲状旁腺功能亢进症可能有多种表现形式,从偶然发现的无症状生化表现到胃肠道、精神、肾脏和骨骼表现,不一而足。由于骨代谢异常,褐色瘤是一种罕见的非肿瘤性病变。在此,我们描述了一名因甲状旁腺腺瘤而出现骨溶解性病变和严重无症状高钙血症的患者:一名38岁的男性患者因上肢和下肢多处骨质病变而疼痛难忍。长骨的X光片显示多发性溶解性病变,皮质变薄。检查显示患有高钙血症和甲状旁腺功能亢进症。放射性核素扫描显示患者患有甲状旁腺腺瘤。患者接受了高钙血症治疗,并进行了甲状旁腺切除术:结论:对于出现多发性骨性肿胀和无症状高钙血症的患者,应怀疑甲状旁腺功能亢进。甲状旁腺腺瘤是原发性甲状旁腺功能亢进症的一个可治疗病因。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
PARATHYROID ADENOMA PRESENTING AS MULTIPLE BROWN TUMORS AND SEVERE ASYMPTOMATIC HYPERCALCEMIA.

Introduction: Primary hyperparathyroidism may have several presentations, varying from an incidental asymptomatic biochemical finding to gastrointestinal, psychiatric, renal and bone manifestations. Brown tumors are rare non-neoplastic lesions because of abnormal bone metabolism. Herein, we describe a patient who presented with lytic bony lesions and severe asymptomatic hypercalcemia due to parathyroid adenoma.

Case presentation: A 38-year-old male presented with multiple painful bony lesions over upper and lower limbs. Radiographs of long bones showed multiple lytic lesions with cortical thinning. Investigations revealed hypercalcemia and hyperparathyroidism. A radionuclide scan showed parathyroid adenoma. The patient was treated for hypercalcemia and a parathyroidectomy was performed.

Conclusions: In a patient presenting with multiple bony swellings and asymptomatic hypercalcemia, hyperparathyroidism should be suspected. Parathyroid adenoma is a treatable cause of primary hyperparathyroidism.

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来源期刊
Acta Endocrinologica-Bucharest
Acta Endocrinologica-Bucharest 医学-内分泌学与代谢
CiteScore
1.30
自引率
20.00%
发文量
53
审稿时长
6-12 weeks
期刊介绍: Acta Endocrinologica (Buc) is an international journal covering the fields of basic and clinical Endocrinology, Neuroendocrinology, Reproductive Medicine, Chronobiology, Human Ethology published quarterly Acta Endocrinologica (Buc) is the official international journal of the Romanian Society for Endocrinology. It continues the former Romanian Journal of Endocrinology
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