[长非编码 RNA 在急性髓性白血病发生和发展中的作用研究进展--综述]。

Q4 Medicine
Xiao-Shi Lu, Xin-Qi Wang, Ying-Nan DU, Ji-Hong Zhang
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引用次数: 0

摘要

近年来,长非编码RNA(lncRNA)在急性髓性白血病(AML)中的重要性引起了广泛关注。其中,起促癌作用的lncRNA主要包括HOTAIR、UCA1、H19、ITGB2-AS1和SNHG家族的一些基因,而起抑癌作用的lncRNA主要包括H22954、NEAT1、SNHG4、LINC01128等。本文综述了lncRNAs在AML发生、发展中的作用,以及与AML耐药和预后评估相关的lncRNAs,以期为AML的诊断和预后分析提供理论依据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Research Progress on Role of Long Non-Coding RNA in Occurrence and Development of Acute Myeloid Leukemia--Review].

In recent years, the importance of long non-coding RNA (lncRNA) in acute myeloid leukemia (AML) has attracted wide attention. Among them, lncRNAs that play a role in promoting cancer mainly include HOTAIR, UCA1, H19, ITGB2-AS1 and some genes of SNHG family, while in tumor suppression mainly include H22954, NEAT1, SNHG4, LINC01128 , etc. This article reviews the role of lncRNAs in the occurrence and development of AML, as well as those related to AML resistance and prognosis assessment, so as to provide a theoretical basis for the diagnosis and prognosis analysis of AML.

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来源期刊
中国实验血液学杂志
中国实验血液学杂志 Medicine-Medicine (all)
CiteScore
0.40
自引率
0.00%
发文量
7331
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