富血小板血浆治疗静脉溃疡临床研究系统综述。

IF 3.8 3区医学 Q2 CELL BIOLOGY

Wound Repair and Regeneration Pub Date : 2024-09-01 Epub Date: 2024-06-24 DOI:10.1111/wrr.13201

Tianbo Shi, Shouci Hu, Jing Hui, Yue Ji, Yalan Zhang

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引用次数: 0

摘要

评估富血小板血浆（PRP）治疗静脉溃疡（VUs）的临床证据。通过 Cochrane Library、Web of Science、Embase 和 PubMed 进行电子检索。使用 AMSTAR-2 评估方法质量。证据质量采用 GRADE 系统进行评估。根据 AMSTAR-2，由于条目 2、4 和 7 的局限性，所纳入综述的方法学质量普遍不足。由于存在偏倚风险和不精确性，结果测量的证据质量不高。总之，PRP 可能对 VU 有治疗作用。然而，由于纳入的系统综述和荟萃分析在方法上存在缺陷，因此必须谨慎对待这一结论。

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An overview of systematic reviews of clinical studies of platelet-rich plasma for venous ulcers.

To evaluate the clinical evidence of platelet-rich plasma (PRP) in the treatment of venous ulcers (VUs). Electronic searches were conducted through the Cochrane Library, Web of Science, Embase and PubMed. AMSTAR-2 was used to assess the methodological quality. The quality of evidence was assessed using the GRADE system. According to AMSTAR-2, the methodological quality of the included reviews was generally inadequate owing to the limitations of entries 2, 4 and 7. Due to bias risk and imprecision, the evidence quality of the outcome measures was inadequate. In conclusion, PRP may have a therapeutic effect on VUs. However, this conclusion must be treated with caution due to methodological flaws of the included systematic reviews and meta-analyses.

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来源期刊

Wound Repair and Regeneration 医学-皮肤病学

CiteScore

5.90

自引率

3.40%

发文量

审稿时长

6-12 weeks

期刊介绍： Wound Repair and Regeneration provides extensive international coverage of cellular and molecular biology, connective tissue, and biological mediator studies in the field of tissue repair and regeneration and serves a diverse audience of surgeons, plastic surgeons, dermatologists, biochemists, cell biologists, and others. Wound Repair and Regeneration is the official journal of The Wound Healing Society, The European Tissue Repair Society, The Japanese Society for Wound Healing, and The Australian Wound Management Association.