心脏移植术后出现重度抑郁障碍，对抗抑郁治疗有部分反应，阿立哌唑增效后病情缓解：病例报告。

IF 2 Q3 NEUROSCIENCES

Neuropsychopharmacology Reports Pub Date : 2024-09-01 Epub Date: 2024-06-25 DOI:10.1002/npr2.12463

Toshinori Nakamura, Yuta Kuraishi, Dai Ohya, Kazuhiro Kimura, Daimei Sasayama, Shinsuke Washizuka

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引用次数: 0

摘要

心脏移植术后重度抑郁障碍（MDD）的发病率很高；然而，当抗抑郁治疗无法改善病情时，却没有关于治疗方案的报道。我们在此报告了一例女性心脏移植术后重度抑郁障碍患者的病例，该患者在接受抗抑郁治疗后病情得到部分改善，但仍有食欲不振的症状。阿立哌唑的辅助治疗改善了她的食欲，她的多发性抑郁症也得到了缓解。当抗抑郁治疗对心脏移植后的 MDD 效果不佳时，应考虑使用阿立哌唑等抗精神病药物进行辅助治疗。

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Major depressive disorder after heart transplantation with partial response to antidepressant therapy and remission with aripiprazole augmentation: A case report.

The incidence of major depressive disorder (MDD) after heart transplantation is high; however, there are no reports on treatment options when antidepressant therapy fails to improve the condition. We herein report on the case of a woman with MDD after heart transplantation who partially improved with antidepressant treatment but continued to have a loss of appetite. Augmentation treatment with aripiprazole improved her appetite, and her MDD went into remission. When antidepressant treatment is not sufficiently effective for MDD after heart transplantation, augmentation treatment with antipsychotics, such as aripiprazole, should be considered.

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来源期刊

Neuropsychopharmacology Reports Psychology-Clinical Psychology

CiteScore

3.60

自引率

4.00%

发文量

审稿时长

14 weeks