抗病毒药物研发的进展：全面了解针对关键病毒蛋白的设计策略和机制。

IF 2.5 4区生物学 Q3 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Journal of microbiology and biotechnology Pub Date : 2024-07-28 Epub Date: 2024-04-29 DOI:10.4014/jmb.2403.03008

Wang Hangyu, Li Panpan, Shen Jie, Wang Hongyan, Wei Linmiao, Han Kangning, Shi Yichen, Wang Shuai, Wang Cheng

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引用次数: 0

摘要

病毒性传染病一直威胁着人类的生存和生活质量，阻碍着人类社会的稳定和进步。因此，研究人员一直致力于开发高效、低毒的抗病毒药物，无论是治疗急性还是慢性传染病。本文从抗病毒药物机制的角度出发，全面回顾了病毒靶向药物的设计理念。旨在为开发新型病毒靶向抗病毒药物提供参考，并指导其临床应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Advancements in Antiviral Drug Development: Comprehensive Insights into Design Strategies and Mechanisms Targeting Key Viral Proteins.

Viral infectious diseases have always been a threat to human survival and quality of life, impeding the stability and progress of human society. As such, researchers have persistently focused on developing highly efficient, low-toxicity antiviral drugs, whether for acute or chronic infectious diseases. This article presents a comprehensive review of the design concepts behind virus-targeted drugs, examined through the lens of antiviral drug mechanisms. The intention is to provide a reference for the development of new, virus-targeted antiviral drugs and guide their clinical usage.

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来源期刊

Journal of microbiology and biotechnology BIOTECHNOLOGY & APPLIED MICROBIOLOGY-MICROBIOLOGY

CiteScore

5.50

自引率

3.60%

发文量

151

审稿时长

2 months

期刊介绍： The Journal of Microbiology and Biotechnology (JMB) is a monthly international journal devoted to the advancement and dissemination of scientific knowledge pertaining to microbiology, biotechnology, and related academic disciplines. It covers various scientific and technological aspects of Molecular and Cellular Microbiology, Environmental Microbiology and Biotechnology, Food Biotechnology, and Biotechnology and Bioengineering (subcategories are listed below). Launched in March 1991, the JMB is published by the Korean Society for Microbiology and Biotechnology (KMB) and distributed worldwide.