Yumei Que, Jiaxin Shi, Zhaowenbin Zhang, Lu Sun, Hairu Li, Xionghai Qin, Zhen Zeng, Xiao Yang, Yanxin Chen, Chong Liu, Chang Liu, Shijie Sun, Qishu Jin, Yanxin Zhang, Xin Li, Ming Lei, Chen Yang, Hai Tian, Jiawei Tian, Jiang Chang
{"title":"封底:离子鸡尾酒疗法通过协同调节结构和电重塑治疗心肌梗死(EXP2 3/2024)","authors":"Yumei Que, Jiaxin Shi, Zhaowenbin Zhang, Lu Sun, Hairu Li, Xionghai Qin, Zhen Zeng, Xiao Yang, Yanxin Chen, Chong Liu, Chang Liu, Shijie Sun, Qishu Jin, Yanxin Zhang, Xin Li, Ming Lei, Chen Yang, Hai Tian, Jiawei Tian, Jiang Chang","doi":"10.1002/EXP.20240302","DOIUrl":null,"url":null,"abstract":"<p>Ion cocktail consisting of silicate, strontium and copper ions significantly reduces the deteriorative electrical and structural remodeling after myocardial infarction by stimulating angiogenesis of endothelial cells and M2 polarization of macrophages, and inhibiting cardiomyocyte apoptosis under hypoxia/ischemic condition. This ion cocktail therapy reveals a new strategy to effectively treat myocardial infarction with clinical translation potential.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":72997,"journal":{"name":"Exploration (Beijing, China)","volume":"4 3","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/EXP.20240302","citationCount":"0","resultStr":"{\"title\":\"Back Cover: Ion cocktail therapy for myocardial infarction by synergistic regulation of both structural and electrical remodeling (EXP2 3/2024)\",\"authors\":\"Yumei Que, Jiaxin Shi, Zhaowenbin Zhang, Lu Sun, Hairu Li, Xionghai Qin, Zhen Zeng, Xiao Yang, Yanxin Chen, Chong Liu, Chang Liu, Shijie Sun, Qishu Jin, Yanxin Zhang, Xin Li, Ming Lei, Chen Yang, Hai Tian, Jiawei Tian, Jiang Chang\",\"doi\":\"10.1002/EXP.20240302\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Ion cocktail consisting of silicate, strontium and copper ions significantly reduces the deteriorative electrical and structural remodeling after myocardial infarction by stimulating angiogenesis of endothelial cells and M2 polarization of macrophages, and inhibiting cardiomyocyte apoptosis under hypoxia/ischemic condition. This ion cocktail therapy reveals a new strategy to effectively treat myocardial infarction with clinical translation potential.\\n\\n <figure>\\n <div><picture>\\n <source></source></picture><p></p>\\n </div>\\n </figure></p>\",\"PeriodicalId\":72997,\"journal\":{\"name\":\"Exploration (Beijing, China)\",\"volume\":\"4 3\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-06-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/EXP.20240302\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Exploration (Beijing, China)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/EXP.20240302\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Exploration (Beijing, China)","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/EXP.20240302","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Back Cover: Ion cocktail therapy for myocardial infarction by synergistic regulation of both structural and electrical remodeling (EXP2 3/2024)
Ion cocktail consisting of silicate, strontium and copper ions significantly reduces the deteriorative electrical and structural remodeling after myocardial infarction by stimulating angiogenesis of endothelial cells and M2 polarization of macrophages, and inhibiting cardiomyocyte apoptosis under hypoxia/ischemic condition. This ion cocktail therapy reveals a new strategy to effectively treat myocardial infarction with clinical translation potential.